Abstract
Enzymes in isolated vascular beds can fully account for the metabolism of angiotensins I and II in vivo. Enzymes in the blood may not be physiologically important.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Skeggs, L. T., Kahn, J. R., and Shumway, N. P., J. Exp. Med., 103, 295 (1956).
Helmer, O. M., Amer. J. Physiol., 188, 571 (1957).
Khairallah, P. A., Bumpus, F. M., Page, I. H., and Smeby, R. R., Science, 140, 672 (1963).
Ng, K. K. F., and Vane, J. R., Nature, 216, 762 (1967).
Ng, K. K. F., and Vane, J. R., Nature, 218, 144 (1968).
Akinkugbe, O. D., Brown, W. C. B., and Cranston, W. I., Clin. Sci., 30, 409 (1966).
Hodge, R. L., Ng, K. K. F., and Vane, J. R., Nature, 215, 138 (1967).
Regoli, E., and Vane, J. R., Brit. J. Pharmacol., 23, 351 (1964).
Paton, W. D. M., J. Physiol., 137, 35P (1957).
Biron, P., Life Sci., 7, 965 (1968).
Thurau, K., Circulation Res., 20, II, 79 (1967).
Britton, K. E., Lancet, ii, 329 (1963).
Biron, P., Clin. Res., 16, 112 (1968).
Biron, P., La Presse, Montreal, December 21, 1968.
Bakhle, Y. S., Nature, 220, 919 (1968).
Ferreira, S. H., Brit. J. Pharmacol., 24, 163 (1965).
Piper, P. J., and Vane, J. R., Florence Symposium, September, 1968, Prostaglandins, Peptides and Amines (Academic Press, London, in the press).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BAKHLE, Y., REYNARD, A. & VANE, J. Metabolism of the Angiotensins in Isolated Perfused Tissues. Nature 222, 956–959 (1969). https://doi.org/10.1038/222956a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/222956a0
This article is cited by
-
Preclinical studies on angiotensin converting enzyme inhibitors
Cardiovascular Drugs and Therapy (1987)
-
Multiple control of inflammation by glucocorticoids
Agents and Actions (1986)
-
Glucocorticoid induction of angiotensin converting enzyme
Agents and Actions (1986)
-
Innervation and vascular pharmacodynamics of the mammalian spleen
Experientia (1985)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
