Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Definition and Antagonism of Histamine H2-receptors

Abstract

H2-receptor antagonist, a new group of drugs, may help to unravel the physiology of histamine and gastrin.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

References

  1. Ash, A. S. F., and Schild, H. O., Brit. J. Pharmacol. Chemother., 27, 427 (1966).

    Article  CAS  Google Scholar 

  2. Loew, E. R., and Chickering, O., Proc. Soc. Exp. Biol. Med., 48, 65 (1941).

    Article  CAS  Google Scholar 

  3. Trendelenburg, U., J. Pharmacol., 130, 450 (1960).

    CAS  Google Scholar 

  4. Dews, P. B., and Graham, J. D. P., Brit. J. Pharmacol. Chemother., 1, 278 (1946).

    Article  CAS  Google Scholar 

  5. Hofmann, K., Imidazole and its Derivatives, 188, (Interscience, New York, 1953).

    Google Scholar 

  6. Finney, D. J., Probit Analysis, 111, (Cambridge University Press, 1962).

    Google Scholar 

  7. Arunlakshana, O., and Schild, H. O., Brit. J. Pharmacol. Chemother., 14, 48 (1959).

    Article  CAS  Google Scholar 

  8. Ariens, E. J., (ed.) Molecular Pharmacology, 1, (Academic Press, London and New York, 1964).

  9. Marquardt, D. W., J. Soc. Indust. Appl. Math., 11 (1963).

  10. Parker, R. B., and Waud, D. R., J. Pharmacol., 177, 1 (1971).

    CAS  Google Scholar 

  11. Waud, D. R., Pharmacol. Rev., 20, 49 (1968).

    CAS  Google Scholar 

  12. Rowlands, C., Temperley, J. T., and Wyllie, J. H., Lancet, ii, 348 (1969).

  13. Folkow, B., Haeger, K., and Kahlson, G., Acta Physiol. Scand., 15, 264 (1948).

    Article  CAS  Google Scholar 

  14. Bain, W. A., Proc. Roy. Soc. Med., 42, 615 (1949).

    CAS  PubMed  Google Scholar 

  15. McIntosh, F. C., Quart. J. Exp. Physiol., 28, 87 (1938).

    Article  Google Scholar 

  16. Code, C. F., Fed. Proc., 24, 1311 (1965).

    CAS  PubMed  Google Scholar 

  17. Johnson, L. R., Gastroenterology, 61, 106 (1971).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BLACK, J., DUNCAN, W., DURANT, C. et al. Definition and Antagonism of Histamine H2-receptors. Nature 236, 385–390 (1972). https://doi.org/10.1038/236385a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/236385a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing