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Polyglutamines, nuclear inclusions and neurodegeneration

Amyloid-like aggregates of expanded polyglutamines are present in nuclei from affected neurons in Huntington and related neurodegenerative diseases.

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Lunkes, A., Mandel, JL. Polyglutamines, nuclear inclusions and neurodegeneration. Nat Med 3, 1201–1202 (1997). https://doi.org/10.1038/nm1197-1201

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