Coexpression of the C-MYC protooncogene with α-fetoprotein and albumin in fetal mouse liver
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Cited by (28)
Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells
2010, Journal of Biological ChemistryCitation Excerpt :Among these genes is α-fetoprotein (Afp), which is widely used as a marker of stem cell differentiation and endoderm lineage specification (17–19). During embryonic development, Afp is expressed concomitant with hepatic determination at the presumptive ventral foregut (20–22). Previously, we found that Foxa1 is an important, hepatic-expressed activator of Afp (23, 24).
A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm
2001, Mechanisms of DevelopmentCitation Excerpt :Afp and alb have been used as markers of hepatocyte differentiation in studies on the processes involved in hepatic development (Cascio and Zaret, 1991; Gualdi et al., 1996; Houssaint, 1980; Jung et al., 1999). Both afp and alb are not detected in situ in the developing liver until approximately 9.5 dpc (Cascio and Zaret, 1991; Schmid and Schulz, 1990; Shiojiri, 1981; Shiojiri et al., 1991). Consequently, their use as hepatic markers for the earliest stages of liver development has required the use of sensitive PCR-based techniques.
Pleiotrophin as a Swiss 3T3 cell-derived potent mitogen for adult rat hepatocytes
1999, Experimental Cell Research
- 1
Ciba-Geigy, CH-4001 Basel, Switzerland
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Institut für Physiologische Chemie, Heinrich-Heine-Universität, W-4000 Düsseldorf, FRG