Abstract
A 44% and 17.5% increase of homocysteine occurred in patients treated either with fenofibrate or bezafibrate. The increase was not explained by changes in vitamin concentrations but may be related to renal function.
Publication types
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Clinical Trial
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Comparative Study
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Letter
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Randomized Controlled Trial
MeSH terms
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Adult
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Bezafibrate / therapeutic use*
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Chromatography, High Pressure Liquid
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Fenofibrate / therapeutic use*
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Folic Acid / blood
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Hematinics / blood
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Homocysteine / blood*
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Humans
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Hyperhomocysteinemia / chemically induced*
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Hypertriglyceridemia / drug therapy*
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Hypolipidemic Agents / therapeutic use*
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Male
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Middle Aged
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Pilot Projects
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Pyridoxine / blood
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Vitamin B 12 / blood
Substances
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Hematinics
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Hypolipidemic Agents
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Homocysteine
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Folic Acid
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Pyridoxine
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Vitamin B 12
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Fenofibrate
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Bezafibrate