Abstract
Erythrocyte membrane Na+-K+ ATPase and Ca++ATPase levels were investigated in 11 women treated with ECT for endogenous depression and 11 age-matched normal control subjects. Pretreatment ATPase levels in depressives were significantly lower than in controls, and increased to control levels after a course of ECT. These data are discussed in terms of the physiology of depressive illness and ECT.
MeSH terms
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Adenosine Triphosphatases / blood*
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Adult
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Bipolar Disorder / enzymology
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Bipolar Disorder / metabolism
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Calcium / metabolism
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Cell Membrane / enzymology
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Depression / blood
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Depression / metabolism
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Depression / therapy*
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Electroconvulsive Therapy*
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Enzyme Activation
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Erythrocytes / enzymology*
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Female
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Humans
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Middle Aged
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Potassium / metabolism
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Sodium / metabolism
Substances
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Sodium
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Adenosine Triphosphatases
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Potassium
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Calcium