Long-term follow-up of oral tolerance induction with HLA-peptide B27PD in patients with uveitis

Ann N Y Acad Sci. 2004 Dec:1029:408-12. doi: 10.1196/annals.1309.048.

Abstract

Oral tolerance induction with peptide B27PD had an ameliorating effect in uveitis patients, which was also observed in the five-year follow-up period. Repeated treatments with peptide B27PD were also effective. Side effects did not occur in this patient group, not even in patients receiving peptide for up to 42 weeks.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adjuvants, Immunologic / therapeutic use*
  • Amino Acid Sequence
  • Follow-Up Studies
  • HLA-B27 Antigen / immunology*
  • Humans
  • Immune Tolerance*
  • Immunity, Mucosal*
  • Peptide Fragments / immunology*
  • Peptide Fragments / therapeutic use
  • Time Factors
  • Uveitis / immunology*
  • Uveitis / therapy
  • Visual Acuity / immunology

Substances

  • Adjuvants, Immunologic
  • HLA-B27 Antigen
  • Peptide Fragments