Clerodane diterpenoids from Salvia splendens

J Nat Prod. 2006 Dec;69(12):1734-8. doi: 10.1021/np068036d.

Abstract

Four new clerodane diterpenoids, salvisplendins A-D (1-4), have been isolated from an acetone extract of the flowers of Salvia splendens, together with an artifact (5), arising from salvisplendin D (4) by addition of diazomethane, and the already known clerodane olearin (6). The structures of the new compounds (1-5) were established mainly by 1D and 2D NMR spectroscopic studies and, in the case of salvisplendin A (1), by chemical correlation with splenolide B (7). Complete 1H and 13C NMR assignments for olearin (6), not published hitherto, are also reported.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diterpenes, Clerodane / chemistry
  • Diterpenes, Clerodane / isolation & purification*
  • Flowers / chemistry
  • Italy
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plants, Medicinal / chemistry*
  • Salvia / chemistry*

Substances

  • Diterpenes, Clerodane