Anti-neoplastic glucuronide prodrug treatment of human tumor cells targeted with a monoclonal antibody-enzyme conjugate

Biochem Pharmacol. 1991 Oct 24;42(10):2062-5. doi: 10.1016/0006-2952(91)90612-9.
No abstract available

MeSH terms

  • Aniline Mustard / analogs & derivatives*
  • Aniline Mustard / pharmacology
  • Antibodies, Monoclonal / immunology
  • Antineoplastic Agents / pharmacology*
  • Enzyme Activation
  • Glucuronidase / pharmacology
  • Humans
  • Prodrugs / pharmacology*
  • Tumor Cells, Cultured / drug effects*
  • Tumor Cells, Cultured / immunology

Substances

  • Antibodies, Monoclonal
  • Antineoplastic Agents
  • Prodrugs
  • p-hydroxyaniline mustard glucuronide, tetra-n-butyl ammonium salt
  • hydroxyaniline mustard
  • Aniline Mustard
  • Glucuronidase