Abstract
The authors report one case of persistent pulmonary hypertension that had hypoxia although receiving treatment with high frequency oscillation, inotropic drugs, blood transfusion, and oral sildenafil for pulmonary vasodilatation. The patient developed hypotension after two doses of oral sildenafil and no response to high dose of inotropic drugs. So aerosolized iloprost was given via endotracheal tube and oxygen saturation improved within 10 minutes. Oxygen was weaned at 36 hours after treatment with this drug and no any side effect was found.
MeSH terms
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Female
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High-Frequency Ventilation
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Humans
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Hypotension / chemically induced
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Iloprost / administration & dosage*
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Infant, Newborn
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Intubation, Intratracheal
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Persistent Fetal Circulation Syndrome / drug therapy*
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Persistent Fetal Circulation Syndrome / therapy
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Piperazines / adverse effects
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Purines / adverse effects
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Sildenafil Citrate
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Sulfones / adverse effects
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Treatment Failure
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Vasodilator Agents / administration & dosage*
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Vasodilator Agents / adverse effects
Substances
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Piperazines
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Purines
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Sulfones
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Vasodilator Agents
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Sildenafil Citrate
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Iloprost