Modulation of longevity by environmental sensing

Cell. 2007 Dec 28;131(7):1231-4. doi: 10.1016/j.cell.2007.12.002.

Abstract

Organisms from bacteria to humans have the capacity to gauge the quality of their respective environments. Recent advances in understanding how various types of environmental conditions are sensed and interpreted by cells and by organisms have established a critical role for these systems in the modulation of physiology, health, and aging.

Publication types

  • Review

MeSH terms

  • Adaptation, Physiological* / genetics
  • Aging / genetics
  • Aging / metabolism
  • Aging / physiology*
  • Animals
  • Environment
  • Evolution, Molecular
  • Genotype
  • Humans
  • Intracellular Signaling Peptides and Proteins / metabolism
  • Longevity* / genetics
  • Phenotype
  • Sensation* / genetics
  • Sensory Receptor Cells / metabolism
  • Signal Transduction* / genetics

Substances

  • Intracellular Signaling Peptides and Proteins