Monitoring ketamine treatment response in a depressed patient via peripheral mammalian target of rapamycin activation

Am J Psychiatry. 2011 Jul;168(7):751-2. doi: 10.1176/appi.ajp.2011.11010128.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adolescent
  • Animals
  • Antidepressive Agents / therapeutic use
  • Depressive Disorder, Major / complications
  • Depressive Disorder, Major / drug therapy*
  • Depressive Disorder, Major / metabolism
  • Drug Resistance
  • Female
  • Humans
  • Ketamine / pharmacology
  • Ketamine / therapeutic use*
  • Middle Aged
  • Phosphorylation
  • Rats
  • Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors
  • Sirolimus / metabolism*
  • Treatment Outcome

Substances

  • Antidepressive Agents
  • Receptors, N-Methyl-D-Aspartate
  • Ketamine
  • Sirolimus