Unabsorbable carbohydrates and diabetes: Decreased post-prandial hyperglycaemia

Lancet. 1976 Jul 24;2(7978):172-4. doi: 10.1016/s0140-6736(76)92346-1.

Abstract

Two test meals were taken in random order on separate days by 8 non-insulin-requiring diabetic volunteers after 14-hour overnight fasts. Addition of 16 g guar and 10 g pectin to the control meal containing 106 g carbohydrate decreased markedly and significantly the rise in blood-glucose between 30 and 90 minutes and also resulted in significantly lower insulin levels between 30 and 120 minutes. When these meals were fed to 3 insulin-dependent diabetic subjects, a similar flattening of the post-prandial glucose rise ensued. This addition of certain forms of dietary fibre to the diet of diabetics significantly decreases post-prandial hyperglycaemia and would be expected to improve the control of blood-glucose concentration.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Blood Glucose / analysis*
  • Cellulose / therapeutic use*
  • Diabetes Mellitus / diet therapy*
  • Diabetes Mellitus / metabolism
  • Dietary Carbohydrates / metabolism
  • Dietary Carbohydrates / therapeutic use*
  • Dietary Fiber / metabolism
  • Dietary Fiber / therapeutic use*
  • Eating
  • Female
  • Humans
  • Insulin / blood
  • Intestinal Absorption
  • Male
  • Mannans / therapeutic use*
  • Middle Aged
  • Pectins / therapeutic use*
  • Polysaccharides / therapeutic use*
  • Time Factors

Substances

  • Blood Glucose
  • Dietary Carbohydrates
  • Dietary Fiber
  • Insulin
  • Mannans
  • Polysaccharides
  • Pectins
  • Cellulose