Topical capsaicin-pharmacology and potential role in the treatment of temporomandibular pain

E V Hersh; R A Pertes; H A Ochs

Topical capsaicin-pharmacology and potential role in the treatment of temporomandibular pain

J Clin Dent. 1994;5(2):54-9.

Authors

E V Hersh¹, R A Pertes, H A Ochs

Affiliation

¹ Department of Oral and Maxillofacial Surgery/Pharmacology, University of Pennsylvania School of Dental Medicine, Philadelphia.

PMID: 7528023

Abstract

Capsaicin is an over-the-counter topical analgesic marketed at 0.025% and 0.075% concentrations. It is currently approved by the United States Food and Drug Administration for the topical relief of pain due to rheumatoid arthritis, osteoarthritis and various neuralgias. This paper will review the basic and clinical pharmacology of capsaicin, and discuss its potential role in the management of pain in the temporomandibular joint region.

Publication types

Review

MeSH terms

Animals
Anti-Inflammatory Agents, Non-Steroidal / pharmacology
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Capsaicin / pharmacology*
Capsaicin / therapeutic use*
Chronic Disease
Facial Pain / drug therapy*
Humans
Nerve Fibers / drug effects
Nerve Fibers / physiology
Substance P / antagonists & inhibitors
Substance P / physiology
Temporomandibular Joint Disorders / drug therapy*

Substances

Anti-Inflammatory Agents, Non-Steroidal
Substance P
Capsaicin