Application of the three-dimensional structures of protein target molecules in structure-based drug design

J Med Chem. 1994 Apr 15;37(8):1035-54. doi: 10.1021/jm00034a001.
No abstract available

Publication types

  • Review

MeSH terms

  • Crystallization
  • Drug Design*
  • HIV Protease Inhibitors / chemistry
  • HIV-1 / enzymology
  • Models, Molecular
  • Molecular Structure
  • Proteins / chemistry*
  • Structure-Activity Relationship
  • Thymidylate Synthase / antagonists & inhibitors

Substances

  • HIV Protease Inhibitors
  • Proteins
  • Thymidylate Synthase