Abstract
Mouse brain-type cannabinoid receptor (CB1) cDNA was cloned and sequenced. Comparison to rat and human CB1 sequences showed extensive homology (>96%) both at the nucleotide and protein levels implicating the importance of this protein in mammalian brain physiology.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Brain / metabolism*
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Cannabinoids / metabolism*
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Cloning, Molecular
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Conserved Sequence
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DNA, Complementary / genetics*
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Humans
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Mice
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Mice, Inbred C57BL
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Molecular Sequence Data
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Rats
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Receptors, Cannabinoid
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Receptors, Drug / genetics*
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Sequence Homology, Amino Acid
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Sequence Homology, Nucleic Acid
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Species Specificity
Substances
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Cannabinoids
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DNA, Complementary
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Receptors, Cannabinoid
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Receptors, Drug