Full-length cDNA sequence of a progesterone membrane-binding protein from porcine vascular smooth muscle cells

E Falkenstein; C Meyer; C Eisen; P C Scriba; M Wehling

doi:10.1006/bbrc.1996.1761

Full-length cDNA sequence of a progesterone membrane-binding protein from porcine vascular smooth muscle cells

Biochem Biophys Res Commun. 1996 Dec 4;229(1):86-9. doi: 10.1006/bbrc.1996.1761.

Authors

E Falkenstein¹, C Meyer, C Eisen, P C Scriba, M Wehling

Affiliation

¹ Institute of Clinical Pharmacology, Faculty of Clinical Medicine at Mannheim, University of Heidelberg, Germany.

PMID: 8954087
DOI: 10.1006/bbrc.1996.1761

Abstract

A full-length cDNA clone for a progesterone membrane binding protein from porcine vascular smooth muscle cells was isolated and the complete nucleotide sequence determined. The cDNA encodes a protein of 194 amino acids with a transmembrane segment. This protein is likely to represent the first steroid membrane receptor or a part of it for which sequence information is available.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Conserved Sequence
DNA, Complementary / genetics
Molecular Sequence Data
Muscle, Smooth, Vascular / chemistry*
Protein Binding
Protein Conformation
RNA, Messenger / genetics
Receptors, Progesterone / genetics*
Receptors, Progesterone / metabolism
Sequence Analysis, DNA
Swine

Substances

DNA, Complementary
RNA, Messenger
Receptors, Progesterone

Associated data

GENBANK/U63315
GENBANK/X99714