Selective cyclooxygenase-2 inhibitors as potential therapeutic agents for inflammatory diseases

Adv Exp Med Biol. 1997:407:157-61. doi: 10.1007/978-1-4899-1813-0_24.
No abstract available

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Anti-Inflammatory Agents, Non-Steroidal / toxicity
  • Bone Neoplasms / enzymology
  • Bone Neoplasms / pathology
  • Cyclooxygenase 1
  • Cyclooxygenase 2
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors / pharmacology
  • Cyclooxygenase Inhibitors / therapeutic use*
  • Cyclooxygenase Inhibitors / toxicity
  • Dinoprostone / biosynthesis
  • Drug Evaluation, Preclinical
  • Humans
  • Indans / pharmacology
  • Indans / toxicity
  • Indomethacin / pharmacology
  • Indomethacin / toxicity
  • Inflammation / drug therapy*
  • Inflammation / metabolism
  • Isoenzymes / antagonists & inhibitors*
  • Isoenzymes / blood
  • Isoenzymes / drug effects*
  • Isoenzymes / physiology
  • Membrane Proteins
  • Neoplasm Proteins / antagonists & inhibitors
  • Osteosarcoma / enzymology
  • Osteosarcoma / pathology
  • Prostaglandin-Endoperoxide Synthases / blood
  • Prostaglandin-Endoperoxide Synthases / drug effects*
  • Prostaglandin-Endoperoxide Synthases / physiology
  • Rats
  • Saimiri
  • Stomach Ulcer / chemically induced
  • Substrate Specificity

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors
  • Indans
  • Isoenzymes
  • L 745337
  • Membrane Proteins
  • Neoplasm Proteins
  • Cyclooxygenase 1
  • Cyclooxygenase 2
  • PTGS1 protein, human
  • PTGS2 protein, human
  • Prostaglandin-Endoperoxide Synthases
  • Ptgs1 protein, rat
  • Dinoprostone
  • Indomethacin