The pharmacology of ryanodine

DJ JENDEN, AS FAIRHURST - Pharmacological Reviews, 1969 - ASPET
… membrane may be inadequate to remove the calcium as it is liberated from an intracellular
site … As others have pointed out, only a fraction of the total calcium appears to be involved in …

[PDF][PDF] Altered [3H] quinuclidinyl benzilate binding in the striatum of rats following chronic cholinesterase inhibition with diisopropylfluorophosphate

…, N KOKKA, AS FAIRHURST - Molecular …, 1980 - researchgate.net
… KOKKA AND AS FAIRHURST. Altered[3H] quinuclidinyl benzilate binding in the striatum
of rats following chronic cholinesterase inhibition with diisopropylfluorophosphate. Mol. …

Calcium efflux from a heavy sarcotubular fraction: effects of ryanodine, caffeine and magnesium

AS Fairhurst, W Hasselbach - European Journal of …, 1970 - Wiley Online Library
… from a homogenate of rabbit skeletal muscle, as described previously [I]. One modification
… When larger initial calcium oxalate loads were required, as in Fig.5, the uptake medium was …

Interactions of D600 (methoxyverapamil) and local anesthetics with rat brain α-adrenergic and muscarinic receptors

AS Fairhurst, ML Whittaker, FJ Ehlert - Biochemical pharmacology, 1980 - Elsevier
… of [3H]QNB binding produced by carbachol, although the inhibition of carbachol binding
produced by the high concentrations of lidocaine was not as great as predicted by the case 1 …

Effect of Carbamazepine on the In Vitro Uptake and Release of Norepinephrine in Adrenergic Nerves of Rabbit Aorta and in Whole Brain Synaptosomes

RE Purdy, RM Julien, AS Fairhurst, MD Terry - Epilepsia, 1977 - Wiley Online Library
… Much of this variability was eliminated in the present study by allowing each tissue to serve
as its own control. The tissue was stimulated twice; drug or control treatment was initiated …

Studies on Metalloflavoproteins. IV. The Role of the Metal1

HR Mahler, AS Fairhurst, B Mackler - Journal of the American …, 1955 - ACS Publications
as well as by a grant of the Nutrition Foundation to Dr. DE Green. A preliminary report of …
strong complexformers such as azide or cyanide, or chelating agents such as the Versenes or …

Effects of dihydropyridine calcium channel blocking drugs on rat brain muscarinic and α-adrenergic receptors

…, M Welcome, A Chhabra, AS Fairhurst - Biochemical …, 1985 - Elsevier
… that the effects on brain receptors occur as a result of direct, … to occur as a result of a common
non-specific action such as … Ca2+ entry blocking drugs such as nifedipine and its analogs …

Naloxone enhancement of acetic acid-induced writhing in rats

N Nokka, AS Fairhurst - Life sciences, 1977 - Elsevier
… In the present study we have employed acetic acid as a prolonged nociceptive stimulus
to produce the writhing response and have shown that prior administration of naloxone …

Effect of ryanodine on the calcium uptake system of skeletal muscle

AS Fairhurst, DJ Jenden - Proceedings of the National …, 1962 - National Acad Sciences
Methods.-A rabbit was killed by cervical fracture and 80 gm of thigh muscle were removed
rapidly, chilled and homogenized in a Sorvall Omnimix for 40 see in an iced medium …

A ryanodine-caffeine-sensitive membrane fraction of skeletal muscle

AS Fairhurst - American Journal of Physiology-Legacy …, 1974 - journals.physiology.org
METHODS The heavy and light muscle fractions were isolated between 2,000-8,000 X g and
12,000-35,000 X g, respectively, from a homogenate of rabbit skeletal muscle as described …