Botanicals and their bioactive phytochemicals for women's health
BM Dietz, A Hajirahimkhan, TL Dunlap… - Pharmacological reviews, 2016 - ASPET
Botanical dietary supplements are increasingly popular for women’s health, particularly for
older women. The specific botanicals women take vary as a function of age. Younger women …
older women. The specific botanicals women take vary as a function of age. Younger women …
[HTML][HTML] Botanical modulation of menopausal symptoms: mechanisms of action?
A Hajirahimkhan, BM Dietz, JL Bolton - Planta medica, 2013 - thieme-connect.com
Menopausal women suffer from a variety of symptoms, including hot flashes and night sweats,
which can affect quality of life. Although it has been the treatment of choice for relieving …
which can affect quality of life. Although it has been the treatment of choice for relieving …
The multiple biological targets of hops and bioactive compounds
JL Bolton, TL Dunlap, A Hajirahimkhan… - Chemical research in …, 2019 - ACS Publications
Botanical dietary supplements for women’s health are increasingly popular. Older women
tend to take botanical supplements such as hops as natural alternatives to traditional hormone …
tend to take botanical supplements such as hops as natural alternatives to traditional hormone …
[HTML][HTML] Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms
A Hajirahimkhan, C Simmler, Y Yuan, JR Anderson… - PloS one, 2013 - journals.plos.org
The increased cancer risk associated with hormone therapies has encouraged many
women to seek non-hormonal alternatives including botanical supplements such as hops (…
women to seek non-hormonal alternatives including botanical supplements such as hops (…
SAR study on estrogen receptor α/β activity of (Iso) flavonoids: importance of prenylation, c-ring (un) saturation, and hydroxyl substituents
…, SG Ellis, RT Hitzman, A Hajirahimkhan… - Journal of agricultural …, 2020 - ACS Publications
Many botanicals used for women’s health contain estrogenic (iso)flavonoids. The literature
suggests that estrogen receptor beta (ERβ) activity can counterbalance estrogen receptor …
suggests that estrogen receptor beta (ERβ) activity can counterbalance estrogen receptor …
Dynamic residual complexity of the isoliquiritigenin–liquiritigenin interconversion during bioassay
C Simmler, A Hajirahimkhan, DC Lankin… - Journal of agricultural …, 2013 - ACS Publications
Bioactive components in food plants can undergo dynamic processes that involve multiple
chemical species. For example, 2′-hydroxychalcones can readily isomerize into flavanones. …
chemical species. For example, 2′-hydroxychalcones can readily isomerize into flavanones. …
Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and …
A Hajirahimkhan, O Mbachu, C Simmler… - Journal of natural …, 2018 - ACS Publications
Postmenopausal women are increasingly using botanicals for menopausal symptom relief
due to the increased breast cancer risk associated with traditional estrogen therapy. The …
due to the increased breast cancer risk associated with traditional estrogen therapy. The …
Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors …
A Hajirahimkhan, C Simmler, H Dong… - Chemical research in …, 2015 - ACS Publications
For the alleviation of menopausal symptoms, women frequently turn to botanical dietary
supplements, such as licorice and hops. In addition to estrogenic properties, these botanicals …
supplements, such as licorice and hops. In addition to estrogenic properties, these botanicals …
Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement
E Krause, Y Yuan, A Hajirahimkhan… - Biomedical …, 2014 - Wiley Online Library
Concerned about the safety of conventional estrogen replacement therapy, women are
using botanical dietary supplements as alternatives for the management of menopausal …
using botanical dietary supplements as alternatives for the management of menopausal …
[HTML][HTML] Breast cancer prevention with liquiritigenin from licorice through the inhibition of aromatase and protein biosynthesis in high-risk women's breast tissue
A Hajirahimkhan, C Howell, ET Bartom, H Dong… - Scientific reports, 2023 - nature.com
Breast cancer risk continues to increase post menopause. Anti-estrogen therapies are
available to prevent postmenopausal breast cancer in high-risk women. However, their adverse …
available to prevent postmenopausal breast cancer in high-risk women. However, their adverse …