Involvement of chemokine receptors in breast cancer metastasis
…, JL Barrera, A Mohar, E Verástegui, A Zlotnik - nature, 2001 - nature.com
Breast cancer is characterized by a distinct metastatic pattern involving the regional lymph
nodes, bone marrow, lung and liver. Tumour cell migration and metastasis share many …
nodes, bone marrow, lung and liver. Tumour cell migration and metastasis share many …
[PDF][PDF] Chemokines: a new classification system and their role in immunity
A Zlotnik, O Yoshie - Immunity, 2000 - cell.com
Japan residues, CXC and CC, depending on whether the first two cysteine residues have
an amino acid between them Chemokines are a group of small (8–14 kDa), mostly(CXC) or …
an amino acid between them Chemokines are a group of small (8–14 kDa), mostly(CXC) or …
[PDF][PDF] The chemokine superfamily revisited
A Zlotnik, O Yoshie - Immunity, 2012 - cell.com
The chemokine superfamily consists of a large number of ligands and receptors. At first
glance, this family appears redundant and their ligand-receptor relationships promiscuous, …
glance, this family appears redundant and their ligand-receptor relationships promiscuous, …
The biology of chemokines and their receptors
D Rossi, A Zlotnik - Annual review of immunology, 2000 - annualreviews.org
During the last five years, the development of bioinformatics and EST databases has been
primarily responsible for the identification of many new chemokines and chemokine receptors…
primarily responsible for the identification of many new chemokines and chemokine receptors…
IL-10 inhibits cytokine production by activated macrophages.
DF Fiorentino, A Zlotnik, TR Mosmann… - … (Baltimore, Md.: 1950 …, 1991 - journals.aai.org
IL-10 inhibits the ability of macrophage but not B cell APC to stimulate cytokine synthesis by
Th1 T cell clones. In this study we have examined the direct effects of IL-10 on both …
Th1 T cell clones. In this study we have examined the direct effects of IL-10 on both …
A new class of membrane-bound chemokine with a CX3C motif
…, W Wang, K Soo, D Rossi, DR Greaves, A Zlotnik… - Nature, 1997 - nature.com
Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key
role in inflammatory and infectious diseases such as AIDS 1–5 . All chemokines studied so …
role in inflammatory and infectious diseases such as AIDS 1–5 . All chemokines studied so …
Chemokines and the arrest of lymphocytes rolling under flow conditions
JJ Campbell, J Hedrick, A Zlotnik, MA Siani… - Science, 1998 - science.org
Circulating lymphocytes are recruited from the blood to the tissue by rolling along the
endothelium until being stopped by a signaling event linked to the G i α subunit of a heterotrimeric …
endothelium until being stopped by a signaling event linked to the G i α subunit of a heterotrimeric …
CCL27–CCR10 interactions regulate T cell–mediated skin inflammation
…, W To, J Sedgwick, T Ruzicka, P Lehmann, A Zlotnik - Nature medicine, 2002 - nature.com
The skin-associated chemokine CCL27 (also called CTACK, ALP and ESkine) and its receptor
CCR10 (GPR-2) mediate chemotactic responses of skin-homing T cells in vitro. Here we …
CCR10 (GPR-2) mediate chemotactic responses of skin-homing T cells in vitro. Here we …
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.
DF Fiorentino, A Zlotnik, P Vieira… - … (Baltimore, Md.: 1950 …, 1991 - journals.aai.org
Murine IL-10 (cytokine synthesis inhibitory factor) inhibits cytokine production by Th1 cell
clones when they are activated under conditions requiring the presence of APC. By …
clones when they are activated under conditions requiring the presence of APC. By …
Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites
…, E Oldham, S Aït-Yahia, F Brière, A Zlotnik… - The Journal of …, 1998 - rupress.org
DCs (dendritic cells) function as sentinels of the immune system. They traffic from the blood
to the tissues where, while immature, they capture antigens. They then leave the tissues and …
to the tissues where, while immature, they capture antigens. They then leave the tissues and …