User profiles for Anthony Falluel-Morel

Anthony Falluel

Assistant Professor in Neuroscience, Rouen Normandy University
Verified email at univ-rouen.fr
Cited by 3592

Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery

D Vaudry, A Falluel-Morel, S Bourgault, M Basille… - Pharmacological …, 2009 - ASPET
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid C-terminally
α-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract …

[PDF][PDF] Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain

…, S Steculorum, A Messina, S Rasika, A Falluel-Morel… - Cell metabolism, 2014 - cell.com
Leptin secreted by adipocytes acts on the brain to reduce food intake by regulating neuronal
activity in the mediobasal hypothalamus (MBH). Obesity is associated with resistance to …

Selenoprotein T: an essential oxidoreductase serving as a guardian of endoplasmic reticulum homeostasis

…, D Cartier, C Bucharles, A Falluel-Morel… - Antioxidants & redox …, 2020 - liebertpub.com
Significance: Selenoproteins incorporate the essential nutrient selenium into their polypeptide
chain. Seven members of this family reside in the endoplasmic reticulum (ER), the exact …

Selenoprotein T is a key player in ER proteostasis, endocrine homeostasis and neuroprotection

Y Anouar, I Lihrmann, A Falluel-Morel… - Free Radical Biology and …, 2018 - Elsevier
Selenoprotein T (SELENOT, SELT) is a thioredoxin-like enzyme anchored at the endoplasmic
reticulum (ER) membrane, whose primary structure is highly conserved during evolution. …

Selenoprotein T exerts an essential oxidoreductase activity that protects dopaminergic neurons in mouse models of Parkinson's disease

…, JJ Bonnet, M Errami, A Falluel-Morel… - Antioxidants & Redox …, 2016 - liebertpub.com
Aims: Oxidative stress is central to the pathogenesis of Parkinson's disease (PD), but the
mechanisms involved in the control of this stress in dopaminergic cells are not fully understood. …

Developmental mercury exposure elicits acute hippocampal cell death, reductions in neurogenesis, and severe learning deficits during puberty

A FalluelMorel, K Sokolowski, HM Sisti… - Journal of …, 2007 - Wiley Online Library
Normal brain development requires coordinated regulation of several processes including
proliferation, differentiation, and cell death. Multiple factors from endogenous and exogenous …

Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death

…, M Basille, A Falluel-Morel… - Proceedings of the …, 2002 - National Acad Sciences
Alcohol exposure during development can cause brain malformations and neurobehavioral
abnormalities. In view of the teratogenicity of ethanol, identification of molecules that could …

The PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human β-cells and its targeted inactivation impairs glucose tolerance

…, D Cartier, S Hassan, A Falluel-Morel… - …, 2013 - academic.oup.com
Selenoproteins are involved in the regulation of redox status, which affects several cellular
processes, including cell survival and homeostasis. Considerable interest has arisen recently …

[HTML][HTML] Characterization of C3a and C5a receptors in rat cerebellar granule neurons during maturation: neuroprotective effect of C5a against apoptotic cell death

…, BJ Gonzalez, MT Schouft, A Falluel-Morel… - Journal of Biological …, 2004 - ASBMB
There is now clear evidence that the Complement anaphylatoxin C3a and C5a receptors (C3aR
and C5aR) are expressed in glial cells, notably in astrocytes and microglia. In contrast, …

Pituitary adenylate cyclase‐activating polypeptide prevents C2‐ceramide‐induced apoptosis of cerebellar granule cells

D Vaudry, A FalluelMorel, M Basille… - Journal of …, 2003 - Wiley Online Library
The sphingolipid metabolites, ceramides, are critical mediators of the cellular stress response
and play an important role in the control of programmed cell death. In particular, ceramides …