Antioxidant superoxide dismutase-a review: its function, regulation in the testis, and role in male fertility
DD Mruk, B Silvestrini, M Mo, CY Cheng - Contraception, 2002 - Elsevier
… For example, rat SOD EX has a low affinity for heparin (type B SOD EX has weak affinity
for heparin), does not bind to heparan sulfate in vivo, and is a dimeric protein [35], [36], [37], [38], …
for heparin), does not bind to heparan sulfate in vivo, and is a dimeric protein [35], [36], [37], [38], …
Environmental toxicants and male reproductive function
… a, b) and BPA (B:a, b) with a Cx26-based GJ communicating channel. The Panel a in A or B
illustrates the top view of the corresponding docked complex and Panel b in A or B illustrates …
illustrates the top view of the corresponding docked complex and Panel b in A or B illustrates …
AF-2364 [1-(2, 4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: a review of recent data
CY Cheng, D Mruk, B Silvestrini, M Bonanomi… - Contraception, 2005 - Elsevier
… Yan Cheng a , Dolores Mruk a , Bruno Silvestrini b , Michele Bonanomi b , Ching-Hang …
3B and M) were similar to serum (Fig. 3A) and all other organs examined (Fig. 3C–L and N–…
3B and M) were similar to serum (Fig. 3A) and all other organs examined (Fig. 3C–L and N–…
Lonidamine, a selective inhibitor of aerobic glycolysis of murine tumor cells
…, MG Paggi, ML Marcante, B Silvestrini… - Journal of the …, 1981 - academic.oup.com
… b For the hepatocytes the values are given for 3XI0· cells. … In: Caputo A, Silvestrini B, eds.
Effects of l-substituted-indazole-3-carboxylic acids on spermatogenesis and cell differentiation …
Effects of l-substituted-indazole-3-carboxylic acids on spermatogenesis and cell differentiation …
Effect of lonidamine on the energy metabolism of Ehrlich ascites tumor cells
…, S D'Atri, C De Martino, ML Marcante, B Silvestrini… - Cancer research, 1981 - AACR
… 1, b and c). They are swollen, and a rarefaction and loss of the matrix is observed. The …
Scorza Barcellona, P., and Silvestrini, B. Morphological and biochemical modifica tions of rat …
Scorza Barcellona, P., and Silvestrini, B. Morphological and biochemical modifica tions of rat …
Morphological, histochemical and biochemical studies on germ cell mitochondria of normal rats
…, PS Barcellona, M Bellocci, B Silvestrini - Cell and tissue …, 1979 - Springer
Morphological changes in rat germ cell mitochondria are described. In diplotene and
secondary spermatocytes and in the spermatids of the Golgi, cap and acrosomal phases, the …
secondary spermatocytes and in the spermatids of the Golgi, cap and acrosomal phases, the …
Two new male contraceptives exert their effects by depleting germ cells prematurely from the testis
CY Cheng, B Silvestrini, J Grima, M Mo… - Biology of …, 2001 - academic.oup.com
… During spermatogenesis, pre- and leptotene spermatocytes differentiated from type B
spermatogonia residing near the basal lamina must translocate across the blood-testis barrier, …
spermatogonia residing near the basal lamina must translocate across the blood-testis barrier, …
Anchoring junctions as drug targets: role in contraceptive development
DD Mruk, B Silvestrini, CY Cheng - Pharmacological reviews, 2008 - ASPET
… in adult mammalian testes, such as the rat, type A spermatogonia in the basal compartment
of the seminiferous epithelium undergo mitotic division to give rise to type B spermatogonia, …
of the seminiferous epithelium undergo mitotic division to give rise to type B spermatogonia, …
A male contraceptive targeting germ cell adhesion
DD Mruk, CH Wong, B Silvestrini, CY Cheng - Nature Medicine, 2006 - nature.com
… This result was also consistent with in vivo data: the serum inhibin B level remained relatively
unaltered as germ cells were depleted from the seminiferous epithelium in rats treated with …
unaltered as germ cells were depleted from the seminiferous epithelium in rats treated with …
Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins
…, WM Lee, CM John, PJ Turek, B Silvestrini… - Human …, 2014 - academic.oup.com
… 1B suggest that cells exposed to a high dose of either toxicant appeared to be retracting
their cytoplasmic processes, and thus perturbing Sertoli cell barrier function. Also, while …
their cytoplasmic processes, and thus perturbing Sertoli cell barrier function. Also, while …