Caveolin-1 is the principal structural protein of caveolae membranes in fibroblasts and
endothelia. Recently, we have shown that the human CAV-1 gene is localized to a suspected …

Among the membrane compartments of a cell, vesicles known as “caveolae” have long defied
functional characterization. However, since the identification of a family of proteins termed “…

We investigated the role of autophagy in atherosclerosis. During plaque formation in mice,
autophagic markers colocalized predominantly with macrophages (mϕ). Atherosclerotic …

Macrophages promote both injury and repair after myocardial infarction, but discriminating
functions within mixed populations remains challenging. Here we used fate mapping, …

Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque.
However, plaque progression renders macrophages unable to degrade exogenous …

The mitochondrial protein MAVS (also known as IPS-1, VISA, and CARDIF) interacts with
RIG-I-like receptors (RLRs) to induce type I interferon (IFN-I). NLRX1 is a mitochondrial …

Cardiac macrophages are crucial for tissue repair after cardiac injury but are not well
characterized. Here we identify four populations of cardiac macrophages. At steady state, resident …

Caveolae organelles and caveolin-1 protein expression are most abundant in adipocytes and
endothelial cells. Our initial report on mice lacking caveolin-1 (Cav-1) demonstrated a loss …

). The implication of such a model is that all plasma membrane proteins are considered to
be uniformly dispersed in the lipid solvent, akin to “icebergs in a sea of lipid.” Many …

Purpose To find out what is known from literature about Long COVID until January 30, 2021.
Methods We undertook a four-step search with no language restriction. A preliminary …