User profiles for Bart Landuyt

Bart Landuyt

KU Leuven
Verified email at tumulus.biz
Cited by 6061

Vascular endothelial growth factor and angiogenesis

ANN Hoeben, B Landuyt, MS Highley, H Wildiers… - Pharmacological …, 2004 - ASPET
Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various
ischemic and inflammatory diseases. A rich variety of pro- and antiangiogenic molecules have …

A comprehensive summary of LL-37, the factotum human cathelicidin peptide

D Vandamme, B Landuyt, W Luyten, L Schoofs - Cellular immunology, 2012 - Elsevier
Cathelicidins are a group of antimicrobial peptides. Since their discovery, it has become
clear that they are an exceptional class of peptides, with some members having pleiotropic …

[HTML][HTML] Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11

…, E Verbeken, B Landuyt, W Landuyt… - British journal of …, 2003 - nature.com
Promising preclinical activity with agents blocking the function of vascular endothelial growth
factor (VEGF) has been observed in various cancer types, especially with combination …

Obestatin does not activate orphan G protein-coupled receptor GPR39

E Lauwers, B Landuyt, L Arckens, L Schoofs… - Biochemical and …, 2006 - Elsevier
Recently, the ligand of the orphan G protein-coupled receptor GPR39 has been identified as
obestatin, a 23-amino acid peptide derived from the ghrelin precursor protein. We used two …

Three‐dimensional cell culture models for anticancer drug screening: Worth the effort?

…, J Doijen, W Luyten, B Landuyt… - Journal of cellular …, 2018 - Wiley Online Library
High attrition of new oncology drug candidates in clinical trials is partially caused by the
poor predictive capacity of artificial monolayer cell culture assays early in drug discovery. …

[PDF][PDF] The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites

…, S El Ashkar, N Malani, FD Bushman, B Landuyt… - Cell reports, 2013 - cell.com
A hallmark of retroviral replication is integration of the viral genome into host cell DNA. This
characteristic makes retrovirus-based vectors attractive delivery vehicles for gene therapy. …

3D spherical microtissues and microfluidic technology for multi-tissue experiments and analysis

…, S Mohanty, P Singh, S Hammad, B Landuyt… - Journal of …, 2015 - Elsevier
Rational development of more physiologic in vitro models includes the design of robust and
flexible 3D-microtissue-based multi-tissue devices, which allow for tissue–tissue interactions…

[PDF][PDF] Isolation and purification of a new kalimantacin/batumin-related polyketide antibiotic and elucidation of its biosynthesis gene cluster

W Mattheus, LJ Gao, P Herdewijn, B Landuyt… - Chemistry & biology, 2010 - cell.com
Kal/bat, a polyketide, isolated to high purity (>95%) is characterized by strong and selective
antibacterial activity against Staphylococcus species (minimum inhibitory concentration, 0.05 …

Molecular mechanisms of LL-37-induced receptor activation: An overview

ET Verjans, S Zels, W Luyten, B Landuyt, L Schoofs - Peptides, 2016 - Elsevier
The human cathelicidin peptide LL-37 plays a crucial role in the immune system on many
levels, from the first line of defense in epithelial cells to restoring the tissue after infection. On …

A multifaceted study of Pseudomonas aeruginosa shutdown by virulent podovirus LUZ19

…, W Cenens, A Aertsen, L Schoofs, B Landuyt… - MBio, 2013 - Am Soc Microbiol
In contrast to the rapidly increasing knowledge on genome content and diversity of bacterial
viruses, insights in intracellular phage development and its impact on bacterial physiology …