User profiles for Bertil B. Fredholm
Bertil FredholmKarolinska I nstitutet Verified email at ki.se Cited by 64569 |
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
BB Fredholm, AP IJzerman, KA Jacobson… - Pharmacological …, 2001 - ASPET
Four adenosine receptors have been cloned and characterized from several mammalian
species. The receptors are named adenosine A 1 , A 2A , A 2B , and A 3 . The A 2A and A 2B …
species. The receptors are named adenosine A 1 , A 2A , A 2B , and A 3 . The A 2A and A 2B …
Actions of caffeine in the brain with special reference to factors that contribute to its widespread use
BB Fredholm, K Bättig, J Holmén, A Nehlig… - Pharmacological …, 1999 - ASPET
Caffeine is the most widely consumed behaviorally active substance in the world. Almost all
caffeine comes from dietary sources (beverages and food), most of it from coffee and tea. …
caffeine comes from dietary sources (beverages and food), most of it from coffee and tea. …
[HTML][HTML] VI. Nomenclature and classification of purinoceptors
BB Fredholm, MP Abbracchio, G Burnstock… - Pharmacological …, 1994 - ncbi.nlm.nih.gov
“Receptors recognize a distinct chemical entity and translate information from that entity into
a form that the cell can read to alter its state”(Kenakin et al., 1992). Even though the …
a form that the cell can read to alter its state”(Kenakin et al., 1992). Even though the …
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors—an update
BB Fredholm, AP IJzerman, KA Jacobson… - Pharmacological …, 2011 - ASPET
In the 10 years since our previous International Union of Basic and Clinical Pharmacology
report on the nomenclature and classification of adenosine receptors, no developments have …
report on the nomenclature and classification of adenosine receptors, no developments have …
Adenosine–dopamine receptor–receptor interactions as an integrative mechanism in the basal ganglia
S Ferré, K Fuxe, BB Fredholm, M Morelli… - Trends in neurosciences, 1997 - cell.com
Increasing evidence suggests that antagonistic interactions between specific subtypes of
adenosine and dopamine receptors in the basal ganglia are involved in the motor depressant …
adenosine and dopamine receptors in the basal ganglia are involved in the motor depressant …
Adenosine receptors as drug targets—what are the challenges?
JF Chen, HK Eltzschig, BB Fredholm - Nature reviews Drug discovery, 2013 - nature.com
Adenosine signalling has long been a target for drug development, with adenosine itself or
its derivatives being used clinically since the 1940s. In addition, methylxanthines such as …
its derivatives being used clinically since the 1940s. In addition, methylxanthines such as …
Adenosine and brain function
BB Fredholm, JF Chen, RA Cunha… - Int Rev …, 2005 - books.google.com
A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …
Adenosine, adenosine receptors and the actions of caffeine
BB Fredholm - Pharmacology & toxicology, 1995 - Wiley Online Library
Of the known biochemical actions of caffeine, only inhibition of adenosine receptors occurs
at concentrations achieved during normal human consumption of the drug. Under normal …
at concentrations achieved during normal human consumption of the drug. Under normal …
Structure and function of adenosine receptors and their genes
BB Fredholm, G Arslan, L Halldner, B Kull… - Naunyn-Schmiedeberg's …, 2000 - Springer
Four adenosine receptors have been cloned from many mammalian and some non-mammalian
species. In each case the translated part of the receptor is encoded by two separate …
species. In each case the translated part of the receptor is encoded by two separate …
Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes.
…, B Johansson, BB Fredholm… - Proceedings of the …, 1991 - National Acad Sciences
Since high-affinity adenosine A2 receptors (A2a) are localized exclusively in dopamine-rich
regions in the central nervous system and mediate inhibition of locomotor activity, we have …
regions in the central nervous system and mediate inhibition of locomotor activity, we have …