User profiles for Bruce L. Zuraw

Bruce Zuraw

University of California San Diego and San Diego VA Healthcare
Verified email at ucsd.edu
Cited by 19059

International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences

…, W Müller-Esterl, DJ Pettibone, BL Zuraw - Pharmacological …, 2005 - ASPET
Kinins are proinflammatory peptides that mediate numerous vascular and pain responses to
tissue injury. Two pharmacologically distinct kinin receptor subtypes have been identified …

Hereditary angioedema

BL Zuraw - New England Journal of Medicine, 2008 - Mass Medical Soc
A 19-year-old woman presents to the emergency department with light-headedness, severe
abdominal pain, and intractable nausea and vomiting that began 12 hours earlier. The …

Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis.

PA Guerne, BL Zuraw, JH Vaughan… - The Journal of …, 1989 - Am Soc Clin Investig
Synovial inflammation is often associated with systemic changes, such as increased levels
of acute phase proteins and hypergammaglobulinemia, which cannot be explained by the …

[HTML][HTML] Nanofiltered C1 inhibitor concentrate for treatment of hereditary angioedema

BL Zuraw, PJ Busse, M White, J Jacobs… - … England Journal of …, 2010 - Mass Medical Soc
Background Hereditary angioedema due to C1 inhibitor deficiency is characterized by
recurrent acute attacks of swelling that can be painful and sometimes life-threatening. Methods …

[HTML][HTML] US HAEA medical advisory board 2020 guidelines for the management of hereditary angioedema

…, MM Frank, HH Li, WR Lumry, BL Zuraw - The Journal of Allergy …, 2021 - Elsevier
Scientific and clinical progress together with the development of effective novel therapeutic
options has engendered multiple important changes in the diagnosis and management of …

Prevention of hereditary angioedema attacks with a subcutaneous C1 inhibitor

…, D Pawaskar, I Pragst, BL Zuraw - New England journal …, 2017 - Mass Medical Soc
Background Hereditary angioedema is a disabling, potentially fatal condition caused by
deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein. In a phase 2 trial, the use of …

[HTML][HTML] TGF-β1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1β but not abrogated by corticosteroids

AM Doerner, BL Zuraw - Respiratory research, 2009 - Springer
Background Chronic persistent asthma is characterized by ongoing airway inflammation
and airway remodeling. The processes leading to airway remodeling are poorly understood, …

Effect of lanadelumab compared with placebo on prevention of hereditary angioedema attacks: a randomized clinical trial

…, JA Bernstein, M Cicardi, HJ Longhurst, BL Zuraw… - Jama, 2018 - jamanetwork.com
Importance Current treatments for long-term prophylaxis in hereditary angioedema have
limitations. Objective To assess the efficacy of lanadelumab, a fully human monoclonal antibody …

[HTML][HTML] Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome CRelease* 210

…, RY Yang, M Schuler, DR Green, BL Zuraw… - Journal of Biological …, 2002 - ASBMB
Galectin-7 is normally expressed in all types of stratified epithelia, but is significantly down-regulated
in squamous cell carcinomas. This protein was recently found to be highly inducible …

[PDF][PDF] Hereditary angioedema with normal C1 inhibitor function: consensus of an international expert panel.

BL Zuraw, K Bork, KE Binkley, A Banerji… - Allergy & Asthma …, 2012 - researchgate.net
… B Zuraw receives grant support from Shire, and is a consultant or speaker for Shire, CSL …
Address correspondence and reprint requests to Bruce L. Zuraw, MD, University of California, …