Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system,
with the potential to either stimulate or inhibit immune responses. Exploiting the immune-…

Dendritic cells and Langerhans cells are specialized for the recognition of pathogens and
have a pivotal role in the control of immunity. As guardians of the immune system, they are …

The realization that dendritic cells (DCs) orchestrate innate and adaptive immune responses
has stimulated research on harnessing DCs to create more effective vaccines. Early clinical …

In the present study we demonstrate that human monocytes activated by lipopolysaccharides
(LPS) were able to produce high levels of interleukin 10 (IL-10), previously designated …

Dendritic cells (DC) capture microorganisms that enter peripheral mucosal tissues and then
migrate to secondary lymphoid organs, where they present these in antigenic form to resting …

Contact between dendritic cells (DC) and resting T cells is essential to initiate a primary
immune response. Here, we demonstrate that ICAM-3 expressed by resting T cells is important …

Cell migration through 3D tissue depends on a physicochemical balance between cell
deformability and physical tissue constraints. Migration rates are further governed by the capacity …

The success of cellular therapies will depend in part on accurate delivery of cells to target
organs. In dendritic cell therapy, in particular, delivery and subsequent migration of cells to …

Recently, we described the cloning and expression of a human cDNA which is the homologue
to P600, a gene transcribed by mouse Th2 clones. Based on its activities on human …

Dendritic cells (DCs) capture Ags or viruses in peripheral tissue to transport them to lymphoid
organs to induce cellular T cell responses. Recently, a DC-specific C-type lectin was …