C1-Esterase inhibitor: an anti-inflammatory agent and its potential use in the treatment of diseases other than hereditary angioedema

C Caliezi, WA Wuillemin, S Zeerleder, M Redondo… - Pharmacological …, 2000 - ASPET
C1-esterase inhibitor (C1-Inh) therapy was introduced in clinical medicine about 25 years ago
as a replacement therapy for patients with hereditary angioedema caused by a deficiency …

Elevated nucleosome levels in systemic inflammation and sepsis

…, LA Aarden, ABJ Groeneveld, C Caliezi… - Critical care …, 2003 - journals.lww.com
… Fever was defined as axillar or rectal temperature of ≥38C and ≥38.3C, respectively ( 13 ).
The diagnosis of SIRS, severe sepsis, and septic shock was established according to the …

C1-inhibitor in patients with severe sepsis and septic shock: beneficial effect on renal dysfunction

C Caliezi, S Zeerleder, M Redondo, B Regli… - Critical care …, 2002 - journals.lww.com
… The complement component C4b/c, a characteristic activation product of the classic
complement pathway, was measured by an enzyme-linked immunosorbent assay by using a …

Administration of C1 inhibitor reduces neutrophil activation in patients with sepsis

S Zeerleder, C Caliezi, G van Mierlo… - Clinical and Vaccine …, 2003 - Am Soc Microbiol
Forty patients with severe sepsis or septic shock recently received C1 inhibitor. In the
present study we studied the effect of C1 inhibitor therapy on circulating elastase-α 1 -antitrypsin …

Activated cytotoxic T cells and NK cells in severe sepsis and septic shock and their role in multiple organ dysfunction

S Zeerleder, CE Hack, C Caliezi, G van Mierlo… - Clinical …, 2005 - Elsevier
To evaluate the role of activated cytotoxic cells in patients with severe sepsis (n = 32) or
septic shock (n = 8), direct (granzymes A and B) as well as indirect markers (cytokines) for …

Performance of a new fibrin monomer assay to exclude deep vein thrombosis in symptomatic outpatients

C Caliezi, N Fünfsinn, T Mauron… - Thrombosis and …, 1999 - thieme-connect.com
In this study we prospectively assessed the reliability of a new fibrin monomer assay in 106
outpatients with clinically suspected deep venous thrombosis of the lower limb. According to …

Rapid D-dimer testing and pre-test clinical probability in the exclusion of deep venous thrombosis in symptomatic outpatients

N Fünfsinn, C Caliezi, FD Biasiutti… - Blood coagulation & …, 2001 - journals.lww.com
We assessed the performance of three rapid D-dimer tests (Auto Dimertest®, VIDAS® and
Tinaquant®) in combination with a pre-test clinical probability model for deep venous …

Agreement of D-dimer results measured by a rapid ELISA (VIDAS) before and after storage during 24 h or transportation of the original whole blood samples

C Caliezi, G Reber, B Lämmle… - Thrombosis and …, 2000 - thieme-connect.com
Fig. 1 Comparison of D-dimer values performed immediately (D-dimer 1) and after storage
at room temperature or transportation (D-dimer 2) of the cited whole blood samples of 117 …

Activation of plasma cascade systems in sepsis: role of C1 inhibitors

S Zeerleder, C Caliezi, M Redondo… - Schweizerische …, 1999 - europepmc.org
During sepsis the complement system, the contact activation system and the coagulation
cascade are activated. Activation of these plasmatic cascades contributes to the development …

Study of the mechanisms involved in hydroxocobalamin interference with determination of some biochemical parameters.

H Gourlain, C Caliez, M Laforge, F Buneaux… - Annales de biologie …, 1994 - europepmc.org
Hydroxocobalamin (OHCo), a red pigment used as an antidote in cyanide poisoning, interferes
with determination of some biochemical parameters. Plasma pools were spiked with two …