Staphylococcus aureus Prosthetic Joint Infection Treated with Debridement and Prosthesis Retention

CM Brandt, WW Sistrunk, MC Duffy… - Clinical Infectious …, 1997 - academic.oup.com
Debridement and retention of the prosthesis was the initial treatment modality in 30 patients
with 33 Staphylococcus aureus prosthetic joint infections (PJIs) who presented to the Mayo …

Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research

W Löscher, C Brandt - Pharmacological reviews, 2010 - ASPET
Diverse brain insults, including traumatic brain injury, stroke, infections, tumors,
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex febrile …

Human Infections Due to Streptococcus dysgalactiae Subspecies equisimilis

JM Hughes, ME Wilson, CM Brandt… - Clinical Infectious …, 2009 - academic.oup.com
Human streptococci that belong to Streptococcus dysgalactiae subspecies equisimilis (SDSE)
have long been known under the name of β-hemolytic groups C and G streptococci. …

[HTML][HTML] Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon

…, K Richter, TM Boeckers, H Potschka, C Brandt… - Neuron, 2003 - cell.com
Mutant mice lacking the central region of the presynaptic active zone protein Bassoon were
generated to establish the role of this protein in the assembly and function of active zones as …

Streptococcus

B Spellerberg, C Brandt - Manual of clinical microbiology, 2015 - Wiley Online Library
The genus Streptococcus currently comprises >100 recognized species, and this number can
certainly be expected to rise with the increasing availability of next‐generation sequencing …

Repeated low-dose treatment of rats with pilocarpine: low mortality but high proportion of rats developing epilepsy

M Glien, C Brandt, H Potschka, H Voigt, U Ebert… - Epilepsy research, 2001 - Elsevier
Systemic administration of pilocarpine in rats can result in a chronic behavioral state that is
similar to human temporal lobe epilepsy. The pilocarpine model of epilepsy is widely used for …

The multidrug transporter hypothesis of drug resistance in epilepsy: proof-of-principle in a rat model of temporal lobe epilepsy

C Brandt, K Bethmann, AM Gastens, W Löscher - Neurobiology of disease, 2006 - Elsevier
Resistance to drug treatment is an important hurdle in the therapy of many diseases, including
cancer, infectious diseases and brain disorders such as epilepsy. A phenotype that is …

Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy

M Glien, C Brandt, H Potschka, W Löscher - Epilepsia, 2002 - Wiley Online Library
Purpose: Animal models in which seizures are elicited by chemical or electrical means are
commonly used for identification and preclinical testing of novel antiepileptic drugs (AEDs). …

Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy

C Brandt, M Nozadze, N Heuchert… - Journal of …, 2010 - Soc Neuroscience
Accumulating evidence suggests that changes in neuronal chloride homeostasis may be
involved in the mechanisms by which brain insults induce the development of epilepsy. A …

Treatment with valproate after status epilepticus: effect on neuronal damage, epileptogenesis, and behavioral alterations in rats

C Brandt, AM Gastens, M zhen Sun, M Hausknecht… - …, 2006 - Elsevier
Epileptogenesis, ie the process leading to epilepsy with spontaneous recurrent seizures, can
be initiated by a number of brain damaging insults, including traumatic brain injury, status …