International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

…, PR Hartig, GR Martin, EJ Mylecharane… - Pharmacological …, 1994 - ASPET
It is evident that in the last decade or so, a vast amount of new information has become
available concerning the various 5-HT receptor types and their characteristics. This derives from …

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

…, PPA Humphrey, DN Middlemiss, EJ Mylecharane… - …, 1986 - Elsevier
As a result of controversy in the literature regarding the classification and nomenclature of
functional receptors for 5-hydroxytryptamine (5-HT), a framework for classification is proposed. …

Ventral tegmental area 5-HT receptors: mesolimbic dopamine release and behavioural studies

EJ Mylecharane - Behavioural brain research, 1995 - Elsevier
Serotoninergic neurones originating in the dorsal and median raphe nuclei project to
mesolimbic structures, including the nucleus accumbens (NAcb) and the ventral tegmental area (…

5-HT2 receptor antagonists and migraine therapy

EJ Mylecharane - Journal of neurology, 1991 - Springer
5-Hydroxytryptamine (5-HT; serotonin) has been implicated in the pathophysiology of migraine,
and several drugs with potent 5-HT 2 receptor blocking activity (methysergide, pizotifen, …

Mechanisms involved in serotonin-induced vasodilatation

EJ Mylecharane - Journal of Vascular Research, 1990 - karger.com
In vitro investigations have identified three major mechanisms which could contribute to the
vasodilator action of serotonin (5-hydroxytryptamine, 5-HT): direct vascular smooth muscle …

Actions of robustoxin, a neurotoxic polypeptide from the venom of the male funnel-web spider (Atrax robustus), in anaesthetized monkeys

EJ Mylecharane, I Spence, DD Sheumack… - Toxicon, 1989 - Elsevier
EJ Mylecharane, I. Spence, DD Sheumack, R. Claassens and MEH Howden. Actions of
robustoxin, a neurotoxic polypeptide from the venom of the male funnel-web spider (Atrax …

Analysis of the heart rate effects of 5-hydroxytryptamine in the cat; mediation of tachycardia by 5-HT1-like receptors

PR Saxena, EJ Mylecharane, J Heiligers - … -Schmiedeberg's archives of …, 1985 - Springer
The effects of 5-hydroxytryptamine (5-HT) on heart rate in anaesthetized cats were analysed
both in intact animals and after spinal section plus vagotomy. The intact cat responded to 5-…

Receptor mechanisms for 5‐hydroxytryptamine in rabbit arteries

…, RJ French, EJ Mylecharane - British Journal of …, 1981 - Wiley Online Library
1 Previous investigations into the vascular actions of biogenic amines implicated in
migraine have shown that the contractile effects of both 5‐hydroxytryptamine (5‐HT) and …

Excitatory 5-hydroxytryptamine receptors in the cat urinary bladder are of the M-and 5-HT2-type.

PR Saxena, J Heiligers, EJ Mylecharane… - Journal of Autonomic …, 1985 - europepmc.org
In anaesthetized cats, a biphasic contraction of the urinary bladder, consisting of an initial
spike followed by a longer-lasting contracture, was elicited by 5-hydroxytryptamine (5-HT) in …

Effects of 5-HT3 receptor-selective agents on locomotor activity in rats following injection into the nucleus accumbens and the ventral tegmental area

DM Gillies, EJ Mylecharane, DM Jackson - European journal of …, 1996 - Elsevier
5-Hydroxytryptamine (5-HT) is involved in the modulation of dopaminergic activity in the
mesolimbic system, but its sites of action and the receptors involved are not well understood. …