User profiles for E. Titus

Erron Titus

Resident Physician in Laboratory Medicine at UCSF
Verified email at ucsf.edu
Cited by 877

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

…, TW Owens, M Gupta, S Pourmal, EW Titus… - Science, 2020 - science.org
INTRODUCTION The emergence of three lethal coronaviruses in <20 years and the urgency
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies, …

[HTML][HTML] Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death

CM Haynes, EA Titus, AA Cooper - Molecular cell, 2004 - cell.com
A variety of debilitating diseases including diabetes, Alzheimer's, Huntington's, Parkinson's,
and prion-based diseases are linked to stress within the endoplasmic reticulum (ER). Using …

Recent developments in the understanding of the pharmacokinetics and mechanism of action of chloroquine

EO Titus - Therapeutic drug monitoring, 1989 - journals.lww.com
Because of the binding of chloroquine to various tissue components and the lysosomotropism
of chloroquine, its pharmacokinetics exhibit large apparent volumes of distribution, partial …

[HTML][HTML] Development and field evaluation of a synthetic mosquito lure that is more attractive than humans

…, L Biswaro, RC Smallegange, E Mbeyela, E Titus… - PloS one, 2010 - journals.plos.org
Background Disease transmitting mosquitoes locate humans and other blood hosts by
identifying their characteristic odor profiles. Using their olfactory organs, the mosquitoes detect …

[PDF][PDF] Human embryonic stem cell-derived cardiomyocytes regenerate the infarcted pig heart but induce ventricular tachyarrhythmias

…, TV Sadikov, J Rothberg, KM Panchalingam, E Titus… - Stem Cell Reports, 2019 - cell.com
… (B–E) Graft myocardium showed evidence of structural … C and E) with increasing sarcomeric
organization and alignment from 2 to 4 weeks post transplantation (B and C versus D and E, …

[HTML][HTML] CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

…, AC Thwin, EW Titus, R Trenker, E Tse… - Research …, 2021 - ncbi.nlm.nih.gov
The SARS-CoV-2 protein Nsp2 has been implicated in a wide range of viral processes, but
its exact functions, and the structural basis of those functions, remain unknown. Here, we …

Chemically functionalized carbon nanotubes and their characterization using thermogravimetric analysis, fourier transform infrared, and raman spectroscopy

E Titus, N Ali, G Cabral, J Gracio… - Journal of Materials …, 2006 - Springer
This article reports key findings on the chemical functionalization of carbon nanotubes (CNT).
The functionalization of chemical vapor-deposited CNT was carried out by treating tubes …

An internal promoter underlies the difference in disease severity between N-and C-terminal truncation mutations of Titin in zebrafish

…, EW Titus, C Yuan, C Shi, S Patchava, E Halper… - elife, 2015 - elifesciences.org
10.7554/eLife.09406.001 Truncating mutations in the giant sarcomeric protein Titin result in
dilated cardiomyopathy and skeletal myopathy. The most severely affected dilated …

[PDF][PDF] Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies

…, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus… - Cell reports, 2019 - cell.com
… (E) Fold change distribution of essential and nonessential gene sets at indicated time points.
(F) Precision-recall curves based on BFs of predefined essential and non-essential gene …

An International Multicenter Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2-Catecholaminergic Polymorphic Ventricular …

K Ng, EW Titus, KV Lieve, TM Roston, A Mazzanti… - Circulation, 2020 - Am Heart Assoc
Background: Genetic variants in calsequestrin-2 (CASQ2) cause an autosomal recessive
form of catecholaminergic polymorphic ventricular tachycardia (CPVT), although isolated …