Amino-acid sequences derived from complementary DMAs encoding the α- and β-subunits
of the GAB A/ benzo diazepine receptor from bovine brain show homology with other ligand-…

The mdx mouse is an X-linked myopathic mutant, an animal model for human Duchenne
muscular dystrophy. In both mouse and man the mutations lie within the dystrophin gene, but …

There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …

A cDNA encoding a novel member of the G-protein-coupled receptor (GCR) superfamily, an
ATP receptor, has been isolated from an embryonic chick whole brain cDNA library by …

The cloning of a human G-protein-coupled receptor (GPCR) that specifically responds to
UDP-glucose and related sugar-nucleotides has been reported recently. This receptor has …

We show that three of the eleven genes of the nematodeCaenorhabditis elegans that
mediate resistance to the nematocide levamisole and to other cholinergic agonists encode …

Adenosine 5′-triphosphate (ATP) and/or related nucleotides act at both ionotrophic (P2X)
and metabotropic (P2Y) receptors. P2X receptors subunits (P2X 1 —P2X 7 ) form ligand-…

When γ -aminobutyric acid (GABA), the major inhibitory neurotransmitter in vertebrate brain,
binds to its receptor it activates a chloride channel. Neurotransmitter action at the GABA A …

The genes of the ionotropic γ-aminobutyric acid receptor (GABR) subunits have shown an
unusual chromosomal clustering, but only now can this be fully specified by analyses of the …

Cognitive impairment occurs in one-third of patients with Duchenne muscular dystrophy, a
lethal X-linked, recessive disease caused by mutations in the dystrophin gene which is …