Metabotropic glutamate receptors: from the workbench to the bedside
Metabotropic glutamate (mGlu) receptors were discovered in the mid 1980s and originally
described as glutamate receptors coupled to polyphosphoinositide hydrolysis. Almost 6500 …
described as glutamate receptors coupled to polyphosphoinositide hydrolysis. Almost 6500 …
Metabotropic glutamate receptors
F Ferraguti, R Shigemoto - Cell and tissue research, 2006 - Springer
… et al. 2004), whereas the mGlu1β splice variant is strongly expressed in CA3 hippocampal
pyramidal neurons, granule cells of the dentate gyrus and lateral hypothalamus (Ferraguti et …
pyramidal neurons, granule cells of the dentate gyrus and lateral hypothalamus (Ferraguti et …
Neuronal circuits of fear extinction
Fear extinction is a form of inhibitory learning that allows for the adaptive control of conditioned
fear responses. Although fear extinction is an active learning process that eventually …
fear responses. Although fear extinction is an active learning process that eventually …
Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1
F Conquet, ZI Bashir, CH Davies, H Daniel, F Ferraguti… - Nature, 1994 - nature.com
… mutant mice (b, d, f). No immunoreactivity for COOH… of CA1 (f). Low (g) and high (h)
magnification photomicrographs of hippocampal sagittal sections of a homozygous mutant showing f-…
magnification photomicrographs of hippocampal sagittal sections of a homozygous mutant showing f-…
A correlation analysis of the regional distribution of central enkephalin and β‐endorphin immunoreactive terminals and of opiate receptors in adult and old male rats …
…, M Zoli, I Ozini, G Toffano, F Ferraguti - Acta Physiologica …, 1986 - Wiley Online Library
By means of semiquantitative immunocytochemistry and quantitative receptor autoradiography
a correlation analysis has been performed on the pre‐ and post‐synaptic features of …
a correlation analysis has been performed on the pre‐ and post‐synaptic features of …
Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS
C Corti, L Aldegheri, P Somogyi, F Ferraguti - Neuroscience, 2002 - Elsevier
Group III metabotropic glutamate receptors (mGluRs) are selectively activated by L-2-amino-4-phosphonobutyrate
(L-AP4), which produces depression of synaptic transmission. The …
(L-AP4), which produces depression of synaptic transmission. The …
Metabotropic glutamate 1 receptor: current concepts and perspectives
F Ferraguti, L Crepaldi, F Nicoletti - Pharmacological reviews, 2008 - ASPET
Almost 25 years after the first report that glutamate can activate receptors coupled to
heterotrimeric G-proteins, tremendous progress has been made in the field of metabotropic …
heterotrimeric G-proteins, tremendous progress has been made in the field of metabotropic …
A tank-based approach to impedance control with variable stiffness
… x = f(q) are the coordinates of the configuration of the end-effector in the task space and are
obtained from the joint positions through the forward kinematic map f(·). The matrices Λ(x) ∈ …
obtained from the joint positions through the forward kinematic map f(·). The matrices Λ(x) ∈ …
Regulating anxiety with extrasynaptic inhibition
… (f) There was no correlation between EPM anxiety behavior and freezing to the CS + and
CS − for the CS-only group (n = 11 mice, CS-only group; freezing to the CS − versus time spent …
CS − for the CS-only group (n = 11 mice, CS-only group; freezing to the CS − versus time spent …
Neuropeptide Y gene therapy decreases chronic spontaneous seizures in a rat model of temporal lobe epilepsy
Temporal lobe epilepsy remains amongst the most common and drug refractory of neurological
disorders. Gene therapy may provide a realistic therapeutic approach alternative to …
disorders. Gene therapy may provide a realistic therapeutic approach alternative to …