[HTML][HTML] Patient-specific induced pluripotent stem-cell models for long-QT syndrome

…, T Dorn, A Goedel, C Höhnke, F Hofmann… - … England Journal of …, 2010 - Mass Medical Soc
Background Long-QT syndromes are heritable diseases associated with prolongation of the
QT interval on an electrocardiogram and a high risk of sudden cardiac death due to …

[PDF][PDF] Nomenclature of voltage-gated calcium channels

EA Ertel, KP Campbell, MM Harpold, F Hofmann… - Neuron, 2000 - cell.com
As new Ca2+ channel genes are cloned, it is apparent that these two alphabetical nomenclatures
will overlap at α1L, which may not mediate an L-type Ca2+ current and Voltage-gated …

A family of hyperpolarization-activated mammalian cation channels

A Ludwig, X Zong, M Jeglitsch, F Hofmann, M Biel - nature, 1998 - nature.com
Pacemaker activity of spontaneously active neurons 1 , 2 , 3 and heart cells 4 , 5 , 6 is controlled
by a depolarizing, mixed Na + /K + current, named I h (or I f in the sinoatrial node of the …

Primary structure and functional expression from complementary DNA of a brain calcium channel

…, A Mikami, J Nakai, P Ruth, E Bosse, F Hofmann… - Nature, 1991 - nature.com
The primary structure of a voltage-dependent cal-cium channel from rabbit brain has been
deduced by cloning and sequencing the complementary DNA. Calcium channel activity …

[PDF][PDF] Nomenclature of voltage-gated sodium channels

AL Goldin, RL Barchi, JH Caldwell, F Hofmann… - Neuron, 2000 - cell.com
Sodium Channels synonyms for many of sodium channel isoforms. To eliminate confusion
resulting from the multiplicity of names, we propose a standardized nomenclature for Voltage-…

The roles of the subunits in the function of the calcium channel

D Singer, M Biel, I Lotan, V Flockerzi, F Hofmann… - Science, 1991 - science.org
Dihydropyridine-sensitive voltage-dependent L-type calcium channels are critical to
excitation-secretion and excitation-contraction coupling. The channel molecule is a complex of the …

Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4−/− mice

…, S Philipp, D Freise, G Droogmans, F Hofmann… - Nature cell …, 2001 - nature.com
Agonist-induced Ca 2+ entry into cells by both store-operated channels and channels
activated independently of Ca 2+-store depletion has been described in various cell types. The …

[HTML][HTML] Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

…, A Konnerth, HC Pape, M Biel, F Hofmann - The EMBO …, 2003 - embopress.org
Hyperpolarization‐activated cation (HCN) channels are believed to be involved in the
generation of cardiac pacemaker depolarizations as well as in the control of neuronal excitability …

[HTML][HTML] Defective smooth muscle regulation in cGMP kinase I‐deficient mice

…, A Mayerhofer, P Ruth, R Fässler, F Hofmann - The EMBO …, 1998 - embopress.org
Regulation of smooth muscle contractility is essential for many important biological processes
such as tissue perfusion, cardiovascular haemostasis and gastrointestinal motility. While …

A 128× 128 CMOS biosensor array for extracellular recording of neural activity

B Eversmann, M Jenkner, F Hofmann… - IEEE Journal of Solid …, 2003 - ieeexplore.ieee.org
Sensor arrays are a key tool in the field of neuroscience for noninvasive recording of the
activity of biological networks, such as dissociated neurons or neural tissue. A high-density …