Recent scientific studies have advanced the notion of chronic inflammation as a major risk
factor underlying aging and age-related diseases. In this review, low-grade, unresolved, …

Exercise is associated with increased ATP need and an enhanced aerobic and/or
anaerobic metabolism, which results in an increased formation of reactive oxygen species (ROS). …

Physical inactivity leads to increased incidence of a variety of diseases and it can be regarded
as one of the end points of the exercise-associated hormesis curve. On the other hand, …

HIV release requires TSG101, a cellular factor that sorts proteins into vesicles that bud into
multivesicular bodies (MVB). To test whether other proteins involved in MVB biogenesis (the …

Low oxygen tension influences tumor progression by enhancing angiogenesis; and histone
deacetylases (HDAC) are implicated in alteration of chromatin assembly and tumorigenesis. …

The quest to create superhard materials rarely strays from the use of high-pressure synthetic
methods, which typically require gigapascals of applied pressure. We report that rhenium …

Conventional lithium-ion liquid-electrolyte batteries are widely used in portable electronic
equipment such as laptop computers, cell phones, and electric vehicles; however, they have …

TSG101 and ALIX both function in HIV budding and in vesicle formation at the multivesicular
body (MVB), where they interact with other Endosomal Sorting Complex Required for …

Emerging pathological evidence indicates that major chronic aging-related diseases such
as atherosclerosis, arthritis, dementia, osteoporosis, and cardiovascular diseases, are …

The hormesis theory purports that biological systems respond with a bell-shaped curve to
exposure to chemicals, toxins, and radiation. Here we extend the hormesis theory to include …