User profiles for Hiroshi Ozaki

hiroshi ozaki

東京大学
Verified email at g.ecc.u-tokyo.ac.jp
Cited by 12213

Calcium movements, distribution, and functions in smooth muscle

H Karaki, H Ozaki, M Hori, M Mitsui-Saito… - Pharmacological …, 1997 - ASPET
Contraction of smooth muscle is regulated by the cytosolic Ca2+ level ([Ca2+] i) b, and the
sensitivity to Ca2+ of the contractile elements in response to changes in the environment …

[HTML][HTML] Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo

…, T Nakamura, K Omori, K Kobayashi, M Hori, H Ozaki… - Plos one, 2015 - journals.plos.org
Histamine is a mediator of allergic inflammation released mainly from mast cells. Although
histamine strongly increases vascular permeability, its precise mechanism under in vivo …

[HTML][HTML] Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced …

T Murata, K Sato, M Hori, H Ozaki, H Karaki - Journal of Biological …, 2002 - ASBMB
In the pulmonary artery isolated from 1-week hypoxia-induced pulmonary hypertensive rats,
endothelial NO production stimulated by carbachol was decreased significantly in in situ …

Bile acid receptor TGR5 agonism induces NO production and reduces monocyte adhesion in vascular endothelial cells

T Kida, Y Tsubosaka, M Hori, H Ozaki… - … , and vascular biology, 2013 - Am Heart Assoc
Objective— TGR5 is a G-protein–coupled receptor for bile acids. So far, little is known about
the function of TGR5 in vascular endothelial cells. Approach and Results— In bovine aortic …

Anti-inflammatory effects of hydroxycinnamic acid derivatives

…, C Chotimarkorn, IM Shafiqul, M Hori, H Ozaki… - Biochemical and …, 2007 - Elsevier
NF-κB family of transcription factors are involved in numerous cellular processes, including
differentiation, proliferation, and inflammation. It was reported that hydroxycinnamic acid …

Upregulation of iNOS by COX-2 in muscularis resident macrophage of rat intestine stimulated with LPS

…, KJ Won, K Sato, H Ozaki… - American Journal …, 2001 - journals.physiology.org
We investigated the effect of lipopolysaccharide (LPS) on the induction of inducible nitric
oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in muscularis resident macrophages of …

Mycalolide B, a novel actin depolymerizing agent.

S Saito, S Watabe, H Ozaki, N Fusetani… - Journal of Biological …, 1994 - Elsevier
We investigated the effects of a novel marine toxin, mycalolide B, on actin polymerization and
actin-activated myosin Mg(2+)-ATPase activity using purified actin and myosin from rabbit …

Lipopolysaccharide induces macrophage migration via prostaglandin D2 and prostaglandin E2

…, Y Urade, H Hirai, M Nakamura, H Ozaki… - … of Pharmacology and …, 2008 - ASPET
Lipopolysaccharide (LPS) produces prostaglandins (PGs) concomitant to eliciting macrophage
migration. We evaluated the role of PGs in initiating the migration of macrophages, …

Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with …

…, T Murata, M Kaminishi, Y Seto, M Hori, H Ozaki - Gut, 2011 - gut.bmj.com
Background The main symptom of postoperative ileus (POI) is an intestinal motility disorder
in which monocytes/macrophages and neutrophils play crucial roles. Prokinetic 5-…

Statin protects endothelial nitric oxide synthase activity in hypoxia-induced pulmonary hypertension

…, H Tsubone, H Karaki, H Ozaki - … , and vascular biology, 2005 - Am Heart Assoc
Objective— We investigated the effects of fluvastatin on hypoxia-induced (1 to 3 weeks, 10%
O 2 ) pulmonary hypertension with focus on endothelial nitric oxide synthase (eNOS) activity…