User profiles for Hiroshi Ozaki
hiroshi ozaki東京大学 Verified email at g.ecc.u-tokyo.ac.jp Cited by 12213 |
Calcium movements, distribution, and functions in smooth muscle
Contraction of smooth muscle is regulated by the cytosolic Ca2+ level ([Ca2+] i) b, and the
sensitivity to Ca2+ of the contractile elements in response to changes in the environment …
sensitivity to Ca2+ of the contractile elements in response to changes in the environment …
[HTML][HTML] Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo
Histamine is a mediator of allergic inflammation released mainly from mast cells. Although
histamine strongly increases vascular permeability, its precise mechanism under in vivo …
histamine strongly increases vascular permeability, its precise mechanism under in vivo …
[HTML][HTML] Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced …
In the pulmonary artery isolated from 1-week hypoxia-induced pulmonary hypertensive rats,
endothelial NO production stimulated by carbachol was decreased significantly in in situ …
endothelial NO production stimulated by carbachol was decreased significantly in in situ …
Bile acid receptor TGR5 agonism induces NO production and reduces monocyte adhesion in vascular endothelial cells
Objective— TGR5 is a G-protein–coupled receptor for bile acids. So far, little is known about
the function of TGR5 in vascular endothelial cells. Approach and Results— In bovine aortic …
the function of TGR5 in vascular endothelial cells. Approach and Results— In bovine aortic …
Anti-inflammatory effects of hydroxycinnamic acid derivatives
NF-κB family of transcription factors are involved in numerous cellular processes, including
differentiation, proliferation, and inflammation. It was reported that hydroxycinnamic acid …
differentiation, proliferation, and inflammation. It was reported that hydroxycinnamic acid …
Upregulation of iNOS by COX-2 in muscularis resident macrophage of rat intestine stimulated with LPS
…, KJ Won, K Sato, H Ozaki… - American Journal …, 2001 - journals.physiology.org
We investigated the effect of lipopolysaccharide (LPS) on the induction of inducible nitric
oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in muscularis resident macrophages of …
oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in muscularis resident macrophages of …
Mycalolide B, a novel actin depolymerizing agent.
S Saito, S Watabe, H Ozaki, N Fusetani… - Journal of Biological …, 1994 - Elsevier
We investigated the effects of a novel marine toxin, mycalolide B, on actin polymerization and
actin-activated myosin Mg(2+)-ATPase activity using purified actin and myosin from rabbit …
actin-activated myosin Mg(2+)-ATPase activity using purified actin and myosin from rabbit …
Lipopolysaccharide induces macrophage migration via prostaglandin D2 and prostaglandin E2
…, Y Urade, H Hirai, M Nakamura, H Ozaki… - … of Pharmacology and …, 2008 - ASPET
Lipopolysaccharide (LPS) produces prostaglandins (PGs) concomitant to eliciting macrophage
migration. We evaluated the role of PGs in initiating the migration of macrophages, …
migration. We evaluated the role of PGs in initiating the migration of macrophages, …
Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with …
Background The main symptom of postoperative ileus (POI) is an intestinal motility disorder
in which monocytes/macrophages and neutrophils play crucial roles. Prokinetic 5-…
in which monocytes/macrophages and neutrophils play crucial roles. Prokinetic 5-…
Statin protects endothelial nitric oxide synthase activity in hypoxia-induced pulmonary hypertension
…, H Tsubone, H Karaki, H Ozaki - … , and vascular biology, 2005 - Am Heart Assoc
Objective— We investigated the effects of fluvastatin on hypoxia-induced (1 to 3 weeks, 10%
O 2 ) pulmonary hypertension with focus on endothelial nitric oxide synthase (eNOS) activity…
O 2 ) pulmonary hypertension with focus on endothelial nitric oxide synthase (eNOS) activity…