Drug excretion in human breast milk: principles, pharmacokinetics and projected consequences

…, B Hilman, PC Jobe, BR Manno, JE Manno… - Clinical …, 1980 - Springer
The excretion of drugs in human breast milk is reviewed with regard to milk production,
composition, feeding patterns and mechanisms of drug transfer into milk. Fundamental principles …

Temporal Indication of Marijuana Use Can Be Estimated From Plasma and Urine Concentrations of Δ9-Tetrahydrocannabinol, 11-Hydroxy-Δ9-Tetrahydrocannabinol, and 11 …

JE Manno, BR Manno, PM Kemp… - Journal of Analytical …, 2001 - academic.oup.com
JE Manno, KE Ferslew, and BR Manno. Urine excretion patterns of cannabinoids and their
clinical applications of the EMIT dau Cannabinoid urine assay for substance abuse treatment. …

Cannabinoids in humans. II. The influence of three methods of hydrolysis on the concentration of THC and two metabolites in urine

…, IK Abukhalaf, JE Manno, BR Manno… - Journal of analytical …, 1995 - academic.oup.com
Glucuronide conjugates of cannabinoids were previously identified in humans. For gas
chromatographic-mass spectrometric (GC-MS) analysis of the unconjugated compounds in …

Cannabinoids in Humans. I. Analysis of Δ9-Tetrahydrocannabinol and Six Metabolites in Plasma and Urine Using GC-MS

…, IK Abukhalaf, JE Manno, BR Manno… - Journal of analytical …, 1995 - academic.oup.com
This report describes a method for the quantitative analysis of Δ 9 -tetrahydrocannabinol
and six of its metabolites, 8α-hydroxy-Δ 9 -tetrahydrocannabinol, 8β-hydroxy-Δ 9 -…

Comparison of efficacy of ginger with various antimotion sickness drugs

…, JE Manno, MJ Wood, BR Manno… - … Practices and Drug …, 1988 - Taylor & Francis
Ginger and several other medications were compared with scopolamine and d-amphetamine
for effectiveness in prevention of motion sickness. Methods: Double-blind techniques were …

Dose‐response analysis of the efJects of tetrahydrocannabinol in man

GF Kiplinger, JE Manno, BE Rodda… - Clinical Pharmacology …, 1971 - Wiley Online Library
Fifteen volunteers smoked marihuana cigarettes under controlled laboratory conditions on
five occasions. The cigarettes were calibrated to deliver doses of 0, 6.25, 12.5, 25, and 50 εg …

Comparative effects of smoking marihuana or placebo on human motor and mental performance

JE Manno, GF Kiplinger, SE Haine… - Clinical …, 1970 - Wiley Online Library
Motor and mental performance was tested after smoking a placebo cigarette and after
smoking a marihuana cigarette calibrated to deliver 5 mg. of delta‐9‐tetrahydrocannabinol. A …

ESTRIP, a BASIC computer program for obtaining initial polyexponential parameter estimates

RD Brown, JE Manno - Journal of Pharmaceutical Sciences, 1978 - Wiley Online Library
A new BASIC exponential stripping program, ESTRIP, allows the relatively rapid calculation
of initial polyexponential parameter estimates, as does the previously published FORTRAN …

The influence of alcohol and marihuana on motor and mental performance

JE Manno, GF Kiplinger, N Scholz… - Clinical …, 1971 - Wiley Online Library
Twelve healthy male volunteers smoked marihuana cigarettes calibrated to deliver 0, 2.5, or
5 mg. of delta‐9‐tetrahydrocannabinol (THC) either alone or in combination with either a …

Single‐dose pharmacokinetics of bupropion in adolescents: effects of smoking status and gender

…, JA Bocchini Jr, JT Wilson, JE Manno - The Journal of …, 2001 - Wiley Online Library
Sustained‐release (SR) bupropion (Zyban®) is approved as a smoking cessation aid for
adults. Since smoking often begins in adolescence, we determined the single‐dose …