User profiles for J. P. Pin

Jean-Philippe Pin

Université de Montpellier
Verified email at igf.cnrs.fr
Cited by 43212

Pharmacology and functions of metabotropic glutamate receptors

PJ Conn, JP Pin - Annual review of pharmacology and …, 1997 - annualreviews.org
… The work of JP Pin is supported by grants from Centre National pour la Recherche
Scientifique (CNRS), EEC (BIO2-CT93-0243 and PL95-0228), the French ministry of Education, …

The metabotropic glutamate receptors: structure and functions

JP Pin, R Duvoisin - Neuropharmacology, 1995 - Elsevier
Glutamate is the main excitatory neurotransmitter in the brain. For many years it has been
considered to act only on ligand-gated receptor channels—termed NMDA, AMPA and kainate …

[HTML][HTML] Molecular tinkering of G protein‐coupled receptors: an evolutionary success

J Bockaert, JP Pin - The EMBO journal, 1999 - embopress.org
Among membrane‐bound receptors, the G protein‐coupled receptors (GPCRs) are certainly
the most diverse. They have been very successful during evolution, being capable of …

The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors

…, M Parmentier, RG Pertwee, JP Pin… - British journal of …, 2021 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …

The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors

…, MA Panaro, RG Pertwee, JP Pin… - British journal of …, 2019 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial
publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 …

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors

JP Pin, T Galvez, L Prézeau - Pharmacology & therapeutics, 2003 - Elsevier
G-protein-coupled receptors (GPCRs) represent one of the largest gene families in the animal
genome. These receptors can be classified into several groups based on the sequence …

Glutamate stimulates inositol phosphate formation in striatal neurones

F Sladeczek, JP Pin, M Récasens, J Bockaert, S Weiss - Nature, 1985 - nature.com
The major excitatory amino acids, glutamate (Glu) and aspartate (Asp), are thought to act at
three receptor subtypes 1 in the mammalian central nervous system (CNS). These are …

Metabotropic glutamate receptors: from the workbench to the bedside

…, F Ferraguti, DD Schoepp, JT Wroblewski, JP Pin - …, 2011 - Elsevier
Metabotropic glutamate (mGlu) receptors were discovered in the mid 1980s and originally
described as glutamate receptors coupled to polyphosphoinositide hydrolysis. Almost 6500 …

International Union of Pharmacology. XLVI. G protein-coupled receptor list

…, TI Bonner, RR Neubig, EM Rosser, JP Pin… - Pharmacological …, 2005 - ASPET
NC-IUPHAR (International Union of Pharmacology Committee on Receptor Nomenclature
and Drug Classification) and its subcommittees provide authoritative reports on the …

Virtual screening workflow development guided by the “receiver operating characteristic” curve approach. Application to high-throughput docking on metabotropic …

N Triballeau, F Acher, I Brabet, JP Pin… - Journal of medicinal …, 2005 - ACS Publications
The “receiver operating characteristic” (ROC) curve method is a well-recognized metric
used as an objective way to evaluate the ability of a given test to discriminate between two …