The discovery by Hench and co-workers 1 of the dramatic improvement in rheumatoid
arthritis induced by the administration of certain steroids of the adrenal cortex and …

Nephrotoxicity, the major complication of long-term therapy with amphotericin B, is
attributed to drug-induced renal vasoconstriction plus a direct toxic action on renal tubules. …

In order to establish criteria for the quantitative assessment of the renal excretion of hydrogen
ion in patients suspected of having renal tubular acidosis, or in their relatives who might …

A defect in ability to lower urine pH in response to ammonium chloride loading in the absence
of systemic acidosis is defined as the syndrome of incomplete renal tubular acidosis. …

METHODS Hemodynamic measurements Circulation time from forepawto medulla was
measured by the interval between the injection of 1 to 2 ml. of 0.1 per cent sodium cyanide …

The experimental results to be presented here deal with the renal component of the multiple
effects in man of acute experimental respiratory alkalosis (hyperventilation) and acidosis (…

… Barker, ES, Clark, JK, and Elkinton, JR Renal excretion of magnesium as influenced by
lactate administration and certain other acute experimental conditions. Fed. Proc. …

Although the concept of tissue buffering was formulated early in the study of acid-base
disturbances, attention in the past has been directed primarily towards the effects of these …

Excerpt In no field of biology and medicine is confusion more rampant and conceptual clarity
more difficult to attain than in the field of acid-base equilibrium. This has been due to a …

In theory the mortality rate from acute tubular necrosis should be low. The reasons for this
are several. First, the damaged renal tubule is able to undergo more or less complete …