Nucleus accumbens dopamine is known to play a role in motivational processes, and
dysfunctions of mesolimbic dopamine may contribute to motivational symptoms of depression and …

Voluntary physical activity and exercise training can favorably influence brain plasticity by
facilitating neurogenerative, neuroadaptive, and neuroprotective processes. At least some of …

Background Over the last several years, it has become apparent that there are critical
problems with the hypothesis that brain dopamine (DA) systems, particularly in the nucleus …

Although the Skinnerian ‘Empirical Law of Effect’ does not directly consider the fundamental
properties of stimuli that enable them to act as reinforcers, such considerations are critical …

In recent years, considerable emphasis has been placed upon the putative role of nucleus
accumbens dopamine systems in appetitive motivation and positive reinforcement. However, …

… ' and Research., John Wiley and Sons, New York, 1964. [7] Cousins, MS and Salamone, JD,
… and Salamone, JD, Pharmacological characterization of performance on a concurrent lever …

According to the dopamine (DA) hypothesis of reward, DA systems in the brain, particularly
in the nucleus accumbens, are thought to directly mediate the rewarding or primary …

An important aspect of motivated behavior is that organisms will perform complex instrumental
behaviors to gain access to stimuli such as food. In the present study, food-deprived rats …

For several decades, it has been suggested that dopamine (DA), especially in nucleus
accumbens, mediates the primary reinforcing characteristics of natural stimuli such as food, as …

… Much of the work cited in this review was supported by a grant to John D. Salamone from
the US NIH/NIMH (MH078023), and to Merce Correa from C. Sanitat GV AP04108. …