Platelets play an important role in the vessel. Following their formation from megakaryocytes,
platelets exist in circulation for 5–7 days and primarily function as regulators of hemostasis …

Platelets are essential for clotting in the blood and maintenance of normal hemostasis. Under
pathologic conditions such as atherosclerosis, vascular injury often results in hyperactive …

… Among these non‐coding RNA s are micro RNA s (mi RNA s), which are small RNA molecules
that modulate protein expression by degrading m RNA or repressing m RNA translation. …

There is little data considering relationships among human RNA, demographic variables,
and primary human cell physiology. The platelet RNA and expression-1 study measured …

Racial differences in the pathophysiology of atherothrombosis are poorly understood. We
explored the function and transcriptome of platelets in healthy black (n = 70) and white (n = 84) …

… The production of the total product and each specific EEQ-EA and EDP-EA regioisomers
were fit to Michaelis–Menten kinetics with the calculated K m , V max and V max /K m values …

Thrombin activates protease-activated receptor-1 (PAR-1) by cleavage of the amino terminus
to unmask a tethered ligand. Although peptide analogs can activate PAR-1, we show that …

The interaction of endothelial cells with extracellular matrix proteins at focal adhesions sites
contributes to the integrity of vascular endothelial barrier. Although focal adhesion kinase (…

We tested the hypothesis that RhoA, a monomeric GTP-binding protein, induces association
of inositol trisphosphate receptor (IP 3 R) with transient receptor potential channel (TRPC1), …

Current treatments to prevent thrombosis, namely anticoagulants and platelets antagonists,
remain complicated by the persistent risk of bleeding. Improved therapeutic strategies that …