Allergic disorders, such as anaphylaxis, hay fever, eczema and asthma, now afflict roughly
25% of people in the developed world. In allergic subjects, persistent or repetitive exposure to …

… In contrast, cotransfection of both halves into cells restores silencing activity (A
Baniahmad, SY Tsai, MJ Tsai, BW O'Malley, unpublished data). Since silencing activity …

▪ Abstract This review focuses on recent progress in our understanding of how mast cells
can contribute to the initiation, development, expression, and regulation of acquired immune …

Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome 1
, 2 , 3 yet their potential involvement in human disease is not well understood 4 , 5 . Recent …

Background The health benefits of leisure-time physical activity are well known, but whether
less exercise than the recommended 150 min a week can have life expectancy benefits is …

… 7 8 9 10 sence or in the presence of 2 x 10-8 M R5020 alone or in combination with 4 x 10-8
M RU-486 and then assayed for CAT activity. (C) SRC-1 is a general coactivator for steroid …

… –1·45] per 10 μg/m 3 ) in confounder model 3. For PM 2·5 concentration, the HR was 1·18
(0·96–1·46) per 5 μg/m 3 , and for traffic load at major roads within 100 m the HR was 1·09 (0·…

Long intergenic noncoding RNAs (lincRNAs) regulate chromatin states and epigenetic
inheritance. Here, we show that the lincRNA HOTAIR serves as a scaffold for at least two distinct …

Steroid receptors and coactivator proteins are thought to stimulate gene expression by
facilitating the assembly of basal transcription factors into a stable preinitiation complex 1 . What …

… We also investigated two traffic intensity variables—traffic intensity on the nearest road (vehicles
per day) and total traffic load on all major roads within a 100 m buffer. We did cohort-…