User profiles for Massimo Locati

Massimo Locati

University of Milan
Verified email at unimi.it
Cited by 53619

Macrophage plasticity and polarization in tissue repair and remodelling

…, MR Galdiero, A Sica, M Locati - The Journal of …, 2013 - Wiley Online Library
Mononuclear phagocyte plasticity includes the expression of functions related to the resolution
of inflammation, tissue repair and remodelling, particularly when these cells are set in an …

The chemokine system in diverse forms of macrophage activation and polarization

…, A Sica, S Sozzani, P Allavena, A Vecchi, M Locati - Trends in …, 2004 - cell.com
Plasticity and functional polarization are hallmarks of the mononuclear phagocyte system.
Here we review emerging key properties of different forms of macrophage activation and …

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

A Mantovani, S Sozzani, M Locati, P Allavena… - Trends in …, 2002 - cell.com
Mononuclear phagocytes are versatile cells that can express different functional programs
in response to microenvironmental signals. Fully polarized M1 and M2 (or alternatively …

[HTML][HTML] Macrophage activation and polarization: nomenclature and experimental guidelines

…, JA Hamilton, LB Ivashkiv, T Lawrence, M Locati… - Immunity, 2014 - cell.com
Description of macrophage activation is currently contentious and confusing. Like the biblical
Tower of Babel, macrophage activation encompasses a panoply of descriptors used in …

[PDF][PDF] Macrophage activation and polarization

FO Martinez, A Sica, A Mantovani, M Locati - Front biosci, 2008 - article.imrpress.com
Locati: Macrophage polarization comes of age. Immunity, 23, 344-6 (2005) 5. Lucey, DR,
M. … Locati: The chemokine system in diverse forms of macrophage activation and …

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

FO Martinez, S Gordon, M Locati… - The Journal of …, 2006 - journals.aai.org
Comprehensive analysis of the gene expression profiles associated with human monocyte-to-macrophage
differentiation and polarization toward M1 or M2 phenotypes led to the …

[HTML][HTML] Macrophage polarization comes of age

A Mantovani, A Sica, M Locati - Immunity, 2005 - cell.com
Functional polarization of macrophages into M1 or M2 cells is an operationally useful,
simplified conceptual framework describing the plasticity of mononuclear phagocytes. Genetic …

Diversity, mechanisms, and significance of macrophage plasticity

M Locati, G Curtale, A Mantovani - Annual Review of Pathology …, 2020 - annualreviews.org
Macrophages are a diverse set of cells present in all body compartments. This diversity is
imprinted by their ontogenetic origin (embryonal versus adult bone marrow–derived cells); the …

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

…, MA Cassatella, M Locati - Proceedings of the …, 2009 - National Acad Sciences
Inflammation involves a coordinated, sequential, and self limiting sequence of events
controlled by positive and negative regulatory mechanisms. Recent studies have shown that …

International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for …

…, GJ Graham, R Horuk, AH Sparre-Ulrich, M Locati… - Pharmacological …, 2014 - ASPET
Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …