Natural variation in human membrane transporter genes reveals evolutionary and functional constraints

…, M de La Cruz, SJ Johns, D Stryke… - Proceedings of the …, 2003 - National Acad Sciences
Membrane transporters maintain cellular and organismal homeostasis by importing nutrients
and exporting toxic compounds. Transporters also play a crucial role in drug response, …

The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics

…, RA Castro, M de la Cruz… - American Journal …, 2006 - journals.physiology.org
The human organic anion transporter, OAT3 (SLC22A8), plays a critical role in renal drug
elimination, by mediating the entry of a wide variety of organic anions, including a number of …

Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1)

…, M de la Cruz, SJ Johns, D Stryke… - Pharmacogenetics …, 2005 - journals.lww.com
Objectives The organic anion transporter, OAT1 (SLC22A6), plays a role in the renal
elimination of many drugs and environmental toxins. The goal of this study was to identify and …

A pharmacogenetic candidate gene study of tenofovir-associated Fanconi syndrome

A Dahlin, M Wittwer, M de la Cruz, JM Woo… - Pharmacogenetics …, 2015 - journals.lww.com
Background Tenofovir disoproxil fumarate (TDF) is a widely used antiretroviral agent with
favorable efficacy, safety, and tolerability profiles. However, renal adverse events, including the …

Functional characterization and haplotype analysis of polymorphisms in the human equilibrative nucleoside transporter, ENT2

…, LL Lagpacan, TR Taylor, M De La Cruz… - Drug metabolism and …, 2006 - ASPET
The equilibrative nucleoside transporter 2 (ENT2; SLC29A2) is a bidirectional transporter
that is involved in the disposition of naturally occurring nucleosides as well as a variety of …

PharmGKB update: I. Genetic variants of the organic cation transporter 2 (OCT2, SLC22A2)

…, J DeYoung, TR Taylor, M De La Cruz… - Pharmacological …, 2003 - pubmed.ncbi.nlm.nih.gov
… 1 , Conrad C Huang, Doug Stryke, Susan J Johns, Michiko Kawamoto, Thomas E Ferrin,
Joseph DeYoung, Travis R Taylor, Melanie De La Cruz, Ira Herskowitz, Kathleen M Giacomini …

[PDF][PDF] PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters

…, TR Taylor, W Chan, M De La Cruz… - Pharmacological …, 2006 - researchgate.net
Pharmacogenetic Significance: Genetic variation in the SLC22 family of solute transporters
may result in altered expression and/or function of transporter proteins that play an important …

[PDF][PDF] PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB …

…, T Taylor, W Chan, M De La Cruz… - Pharmacological …, 2006 - researchgate.net
Pharmacogenetic Significance: Genetic variation in the SLC6, SLC17, and SLC18 families
of neurotransmitter transporters may result in altered expression and/or function of proteins (…

[BOOK][B] A comparative study on the role of religious interest groups in the formulation of educational policies in the Philippines and Malaysia

RMP De La Cruz - 1989 - search.proquest.com
Religious interest groups play a significant role in the formulation and/or implementation of
educational policies in the Philippines and Malaysia. In the Philippines, the groups are very …

[HTML][HTML] Racism during pregnancy and birthing: experiences from Asian and Pacific Islander, Black, Latina, and Middle Eastern women

TT Nguyen, S Criss, M Kim, MM De La Cruz… - Journal of Racial and …, 2023 - Springer
Background Despite persistent racial disparities in maternal health in the USA, there is
limited qualitative research on women’s experiences of discrimination during pregnancy and …