Natural variation in human membrane transporter genes reveals evolutionary and functional constraints
…, M de La Cruz, SJ Johns, D Stryke… - Proceedings of the …, 2003 - National Acad Sciences
Membrane transporters maintain cellular and organismal homeostasis by importing nutrients
and exporting toxic compounds. Transporters also play a crucial role in drug response, …
and exporting toxic compounds. Transporters also play a crucial role in drug response, …
The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics
…, RA Castro, M de la Cruz… - American Journal …, 2006 - journals.physiology.org
The human organic anion transporter, OAT3 (SLC22A8), plays a critical role in renal drug
elimination, by mediating the entry of a wide variety of organic anions, including a number of …
elimination, by mediating the entry of a wide variety of organic anions, including a number of …
Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1)
…, M de la Cruz, SJ Johns, D Stryke… - Pharmacogenetics …, 2005 - journals.lww.com
Objectives The organic anion transporter, OAT1 (SLC22A6), plays a role in the renal
elimination of many drugs and environmental toxins. The goal of this study was to identify and …
elimination of many drugs and environmental toxins. The goal of this study was to identify and …
A pharmacogenetic candidate gene study of tenofovir-associated Fanconi syndrome
Background Tenofovir disoproxil fumarate (TDF) is a widely used antiretroviral agent with
favorable efficacy, safety, and tolerability profiles. However, renal adverse events, including the …
favorable efficacy, safety, and tolerability profiles. However, renal adverse events, including the …
Functional characterization and haplotype analysis of polymorphisms in the human equilibrative nucleoside transporter, ENT2
…, LL Lagpacan, TR Taylor, M De La Cruz… - Drug metabolism and …, 2006 - ASPET
The equilibrative nucleoside transporter 2 (ENT2; SLC29A2) is a bidirectional transporter
that is involved in the disposition of naturally occurring nucleosides as well as a variety of …
that is involved in the disposition of naturally occurring nucleosides as well as a variety of …
PharmGKB update: I. Genetic variants of the organic cation transporter 2 (OCT2, SLC22A2)
…, J DeYoung, TR Taylor, M De La Cruz… - Pharmacological …, 2003 - pubmed.ncbi.nlm.nih.gov
… 1 , Conrad C Huang, Doug Stryke, Susan J Johns, Michiko Kawamoto, Thomas E Ferrin,
Joseph DeYoung, Travis R Taylor, Melanie De La Cruz, Ira Herskowitz, Kathleen M Giacomini …
Joseph DeYoung, Travis R Taylor, Melanie De La Cruz, Ira Herskowitz, Kathleen M Giacomini …
[PDF][PDF] PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters
…, TR Taylor, W Chan, M De La Cruz… - Pharmacological …, 2006 - researchgate.net
Pharmacogenetic Significance: Genetic variation in the SLC22 family of solute transporters
may result in altered expression and/or function of transporter proteins that play an important …
may result in altered expression and/or function of transporter proteins that play an important …
[PDF][PDF] PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB …
…, T Taylor, W Chan, M De La Cruz… - Pharmacological …, 2006 - researchgate.net
Pharmacogenetic Significance: Genetic variation in the SLC6, SLC17, and SLC18 families
of neurotransmitter transporters may result in altered expression and/or function of proteins (…
of neurotransmitter transporters may result in altered expression and/or function of proteins (…
[BOOK][B] A comparative study on the role of religious interest groups in the formulation of educational policies in the Philippines and Malaysia
RMP De La Cruz - 1989 - search.proquest.com
Religious interest groups play a significant role in the formulation and/or implementation of
educational policies in the Philippines and Malaysia. In the Philippines, the groups are very …
educational policies in the Philippines and Malaysia. In the Philippines, the groups are very …
[HTML][HTML] Racism during pregnancy and birthing: experiences from Asian and Pacific Islander, Black, Latina, and Middle Eastern women
Background Despite persistent racial disparities in maternal health in the USA, there is
limited qualitative research on women’s experiences of discrimination during pregnancy and …
limited qualitative research on women’s experiences of discrimination during pregnancy and …