… This “special substance” was isolated and purified in 1984 by Glenner & Wong (1984), who
… The peptide isolated by Glenner & Wong has come to be known as the Aβ peptide, short for …

The generation of amyloid β-peptide (Aβ) by enzymatic cleavages of the β-amyloid precursor
protein (APP) has been at the center of Alzheimer’s disease (AD) research. While the basic …

The β-amyloid (Aβ) peptide is the major constituent of amyloid plaques in Alzheimer's
disease (AD) brain and is likely to play a central role in the pathogenesis of this devastating …

Objective: Our study examined the stress level and psychological distress of severe acute
respiratory syndrome (SARS) survivors 1 year after the outbreak. Method: During the SARS …

Background Information on the clinical features of the severe acute respiratory syndrome (SARS)
will be of value to physicians caring for patients suspected of having this disorder. …

Mutations in Cu/Zn superoxide dismutase (SOD1) cause a subset of cases of familial
amyotrophic lateral sclerosis. Four lines of mice accumulating one of these mutant proteins (G37R) …

Two β-secretases, BACE1 and BACE2, are involved in generation of Alzheimer's disease
Aβ peptides 1, 2, 3. We report that secretion of Aβ peptides (Aβ1–40/42 and Aβ11–40/42) is …

Previous reports have demonstrated the growth of undifferentiated human embryonic stem (HES)
cells on mouse embryonic fibroblast (MEF) feeders and on laminin- or Matrigel-coated …

Approximately 10% of cases of Alzheimer's disease are familial and associated with autosomal
dominant inheritance of mutations in genes encoding the amyloid precursor protein 1 , …

We have demonstrated the existence of two distinct subtypes of the angiotensin II receptor
in the rat adrenal gland using radioligand binding and tissue section autoradiography. The …