User profiles for P. Kannankeril

Prince Kannankeril

Professor, Vanderbilt University
Verified email at vumc.org
Cited by 11367

HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by …

…, J Brugada, CE Chiang, H Huikuri, P Kannankeril… - Heart rhythm, 2013 - Elsevier
This international consensus statement is the collaborative effort of three medical societies
representing electrophysiology in North America, Europe and Asian-Pacific area: the Heart …

Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes

…, J Brugada, CE Chiang, H Huikuri, P Kannankeril… - Europace, 2013 - academic.oup.com
… Behr, Charles Berul, Nico Blom, Josep Brugada, Chern-En Chiang, Heikki Huikuri, Prince
Kannankeril, Andrew Krahn, Antoine Leenhardt, Arthur Moss, Peter J. Schwartz, Wataru …

Assessment of autonomic function in cardiovascular disease: physiological basis and prognostic implications

MK Lahiri, PJ Kannankeril, JJ Goldberger - Journal of the American college …, 2008 - jacc.org
Certain abnormalities of autonomic function in the setting of structural cardiovascular disease
have been associated with an adverse prognosis. Various markers of autonomic activity …

Drug-induced long QT syndrome

P Kannankeril, DM Roden, D Darbar - Pharmacological reviews, 2010 - ASPET
The drug-induced long QT syndrome is a distinct clinical entity that has evolved from an
electrophysiologic curiosity to a centerpiece in drug regulation and development. This evolution …

Assessment of parasympathetic reactivation after exercise

…, FK Le, M Lahiri, PJ Kannankeril… - American Journal …, 2006 - journals.physiology.org
The objective of this study was to evaluate whether heart rate variability (HRV) can be used
as an index of parasympathetic reactivation after exercise. Heart rate recovery after exercise …

Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia

C van der Werf, PJ Kannankeril, F Sacher… - Journal of the American …, 2011 - jacc.org
Objectives : This study evaluated the efficacy and safety of flecainide in addition to conventional
drug therapy in patients with catecholaminergic polymorphic ventricular tachycardia (…

Cardiac Sodium Channel (SCN5A) Variants Associated with Atrial Fibrillation

D Darbar, PJ Kannankeril, BS Donahue, G Kucera… - Circulation, 2008 - Am Heart Assoc
Background— Genetic studies have identified ion channel gene variants in families segregating
atrial fibrillation (AF), the most common arrhythmia in clinical practice. Here, we tested …

Parasympathetic effects on heart rate recovery after exercise

PJ Kannankeril, FK Le, AH Kadish… - Journal of …, 2004 - journals.sagepub.com
… Despite faster heart rates with parasympathetic blockade, the P–R interval was shorter (p <
.002… significant changes in both the slope (p < .0001) and the intercept (p < .0001), consistent …

Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation

…, S Makino, MF Sinner, PJ Kannankeril… - European heart …, 2009 - academic.oup.com
… age in the FHS (P = 0.0065), but not in the RS (P = 0.62). There was no significant interaction
between rs10033464 genotype and age in the FHS (P = 0.24) or in the RS (P = 0.47). In …

Mutations in sodium channel β1-and β2-subunits associated with atrial fibrillation

…, S Chopra, BS Donahue, PJ Kannankeril… - Circulation …, 2009 - Am Heart Assoc
… In our experiments, wild-type β1 increased SCN5A currents and modulated channel
gating, and the p.R85H and p.D153N mutants showed loss of β1 function with significantly …