Apelin and its G protein-coupled receptor (GPCR) have emerged as a key signalling pathway
in the cardiovascular system. The peptide is a potent inotropic agent and vasodilator. …

A new generalized Reynolds equation, which can incorporate most of the rheological laws
found in the literature, is derived in this paper. A number of numerical solutions of the line …

Background: Elabela/toddler (ELA) is a critical cardiac developmental peptide that acts
through the G-protein–coupled apelin receptor, despite lack of sequence similarity to the …

With the development of surface processing techniques, applications of bearing components
have been introduced with specific surface textures to take advantage of lubrication. An …

[Pyr 1 ]apelin-13 is an endogenous vasodilator and inotrope but is downregulated in pulmonary
hypertension and heart failure, making the apelin receptor an attractive therapeutic target…

Rationale: Mutations in bone morphogenetic protein receptor type II (BMPR-II) underlie most
cases of heritable pulmonary arterial hypertension (PAH). However, disease penetrance is …

Vascular calcification is associated with atherosclerosis, chronic kidney disease, and diabetes,
and results from processes resembling endochondral or intramembranous ossification, or …

A meshing of a gear is a typical example where non-stationary condition exists. Load, velocity,
curvature of meshing point vary along the line of action at any time. A complete numerical …

Human genetics, biomarker, and animal studies implicate loss of function in bone
morphogenetic protein (BMP) signaling and maladaptive transforming growth factor–β (TGFβ) …

Experimental results of steady dimples measured in elliptical glass-steel contact under pure
sliding conditions are presented. It is found that two dimples connected with a shallower …