The brain and the immune system are the two major adaptive systems of the body. During an
immune response the brain and the immune system “talk to each other” and this process is …

Interleukin-6, an inflammatory cytokine, is characterized by pleiotropy and redundancy of
action. Apart from its hematologic, immune, and hepatic effects, it has many endocrine and …

Glucocorticoids are pleiotropic hormones that at pharmacologic doses prevent or suppress
inflammation and other immunologically mediated processes. At the molecular level, …

… Raymond, RL Wilder's work on generalized manifolds-an appreciation, in Geometric and
Algebraic Topology, ed. K. Millett, Proceedings of the Santa Barbara Conference, Lecture …

The revised criteria for the classification of rheumatoid arthritis (RA) were formulated from a
computerized analysis of 262 contemporary, consecutively studied patients with RA and 262 …

Several studies indicate that nonsteroidal anti-inflammatory drugs including indomethacin,
aspirin, sulindac, and piroxicam reduce the risk of colon cancer. Furthermore, nonsteroidal …

… Wilder envisions mathematics as a broad cultural phenomenon. His treatment examines
and illustrates how such concepts as number and length were affected by historic and social …

This classic undergraduate text by an eminent educator acquaints students with the
fundamental concepts and methods of mathematics. In addition to introducing many noteworthy …

High levels of immunoreactive cyclooxygenase (Cox; prostaglandin H synthase) are present
in synovia from patients with rheumatoid arthritis (RA). We now show that the recently …

Inbred Lewis (LEW/N) female rats develop an arthritis in response to group A streptococcal
cell wall peptidoglycan polysaccharide (SCW), which mimics human rheumatoid arthritis. …