The biochemistry of the visual cycle
RR Rando - Chemical Reviews, 2001 - ACS Publications
Vertebrate vision begins with the absorption of light by rhodopsin, causing its 11-cis-retinal
Schiff base chromophore to photoisomerize into its all-trans form. All-trans-retinal is liberated …
Schiff base chromophore to photoisomerize into its all-trans form. All-trans-retinal is liberated …
The chemistry of vitamin A and vision
RR Rando - Angewandte Chemie International Edition in …, 1990 - Wiley Online Library
… Rando has worked on the development of new kinds of mechanism-based inhibitors and
also discovered natural products which follow this mechanistic paradigm. His recent work has …
also discovered natural products which follow this mechanistic paradigm. His recent work has …
[HTML][HTML] Molecular and biochemical characterization of lecithin retinol acyltransferase
…, A Winston, YH Lim, BA Gilbert, RR Rando… - Journal of Biological …, 1999 - ASBMB
The enzyme responsible for conversion of all-trans-retinol into retinyl esters, the lecithin retinol
acyltransferase (LRAT) has been characterized at the molecular level. The cDNA coding …
acyltransferase (LRAT) has been characterized at the molecular level. The cDNA coding …
Specific binding of aminoglycoside antibiotics to RNA
Y Wang, RR Rando - Chemistry & biology, 1995 - cell.com
Background: Aminoglycoside antibiotics interfere with ribosomal protein synthesis and with
intron splicing. Various lines of evidence suggest that RNA is the molecular target for …
intron splicing. Various lines of evidence suggest that RNA is the molecular target for …
The nature of protein kinase C activation by physically defined phospholipid vesicles and diacylglycerols.
LT Boni, RR Rando - Journal of Biological Chemistry, 1985 - ASBMB
Protein kinase C is activated by a 1,2-sn-diacylglycerol and phospholipid at low calcium
concentrations. Of the various phospholipids studied, phosphatidylserine has been shown to be …
concentrations. Of the various phospholipids studied, phosphatidylserine has been shown to be …
Specificity of aminoglycoside binding to RNA constructs derived from the 16S rRNA decoding region and the HIV-RRE activator region
Y Wang, K Hamasaki, RR Rando - Biochemistry, 1997 - ACS Publications
… Wang and RR Rando, unpublished experiments) with similar affinities. In fact, the TAR RNA
… Wang and RR Rando, unpublished experiments). In this context, it is of further interest to …
… Wang and RR Rando, unpublished experiments). In this context, it is of further interest to …
Specific binding of aminoglycosides to a human rRNA construct based on a DNA polymorphism which causes aminoglycoside-induced deafness
K Hamasaki, RR Rando - Biochemistry, 1997 - ACS Publications
RNA constructs prepared from wild-type and mutant (1555 G ) human mitochondrial 12S
RNA were studied with respect to their abilities to specifically bind aminoglycoside antibiotics. …
RNA were studied with respect to their abilities to specifically bind aminoglycoside antibiotics. …
Retinal tubulin binds macular carotenoids.
…, NA Balashov, ED Tsong, RR Rando - … & visual science, 1997 - iovs.arvojournals.org
… Bernstein PS, Choi SY, Ho YC, Rando RR. Photoaffinity labeling of retinoic acid-binding
proteins. Proc NatAcadSci USA.1995;92:654-658. …
proteins. Proc NatAcadSci USA.1995;92:654-658. …
[HTML][HTML] A palmitoylation switch mechanism in the regulation of the visual cycle
L Xue, DR Gollapalli, P Maiti, WJ Jahng, RR Rando - Cell, 2004 - cell.com
RPE65 is essential for the biosynthesis of 11-cis-retinal, the chromophore of rhodopsin.
Here, we show that the membrane-associated form (mRPE65) is triply palmitoylated and is a …
Here, we show that the membrane-associated form (mRPE65) is triply palmitoylated and is a …
Membrane phospholipids as an energy source in the operation of the visual cycle
RR Rando - Biochemistry, 1991 - ACS Publications
… 3H]-£j//-tra/zs-retinol plus [15]4C\-all-trans-Tctim\ was administered to either rats or frogs (Bernstein
& Rando, 1986). If isomerization occurs at the aldehyde level of oxidation, than half …
& Rando, 1986). If isomerization occurs at the aldehyde level of oxidation, than half …